ArticleRomanian journal of anaesthesia and intensive care2021
Blood Rheology Alterations in Patients with Cardiovascular Diseases.
Article in Romanian journal of anaesthesia and intensive care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Multi-target mechanisms and therapeutic potential of Dahuang Zhechong pill in lower extremity peripheral artery disease: a structured narrative review.Frontiers in pharmacology · 2026Review
- Association between fibrinogen and decline in cardiorespiratory fitness in patients undergoing cardiopulmonary exercise testing: a large cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- Seasonal Variations in Estimated Whole Blood Viscosity Associated with HbA1c: Evidence from Retrospective Pathology Review for Diabetes Management.International journal of molecular sciences · 2025Observational
- Evaluation of Whole Blood Viscosity to Predict Stent Restenosis in Patients with Coronary Artery Disease.Anatolian journal of cardiology · 2025Article
- Mechanical Stimulation of Red Blood Cells Aging: Focusing on the Microfluidics Application.Micromachines · 2025Review
- Integrated effects of cold acclimation: physiological mechanisms, psychological adaptations, and potential applications.Frontiers in physiology · 2025Review
- COVID-19 and silent hypoxemia in a minimal closed-loop model of the respiratory rhythm generator.Biological cybernetics · 2024Article
- Biomimicking Atherosclerotic Vessels: A Relevant and (Yet) Sub-Explored Topic.Biomimetics (Basel, Switzerland) · 2024Review
- Influence of a Decrease in Blood Viscosity on Arterial Pressure in Normotensive and Spontaneously Hypertensive Rats.Bulletin of experimental biology and medicine · 2024Article
- A bio-fabricated tesla valves and ultrasound waves-powered blood plasma viscometer.Frontiers in bioengineering and biotechnology · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood rheology is an important determinant of blood flow but is probably one of the most neglected areas in clinical literature and practice. Blood viscosity changes according to shear rates and depends on cellular and plasma factors. RBCs' aggregability and deformability are the main determinants of local flow characteristics in areas with lower and higher shear rates, but plasma viscosity is the main regulatory factor of flow resistance in the microcirculation. In individuals with altered blood rheology, the mechanical stress to vascular walls induces endothelial injury and vascular remodelling, and promotes atherosclerosis. Increased values of whole blood viscosity and plasma viscosity are correlated with cardiovascular risk factors and adverse cardiovascular events. The long-term effects of physical exercise can produce a hemorheological fitness that protects against cardiovascular diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.