Evidence map›Paper›PMID 36843817›Full record

ArticleCureus2023

Evaluating Patterns of Injectate Spread After Rectus Sheath Block: A Cadaveric Dissection Study.

Andres Rojas, Daniel T McMillan, Jennifer D Allan, Monika Nanda, Chinwe Anumudu, Jeremy Armbruster, Maxwell Jolly, Justin Magin, Gisselle Maquoit, Stuart A Grant

Abstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Observational
  4. Review
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andres RojasAnesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.
Daniel T McMillanAnesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.
Jennifer D AllanAnesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.
Monika NandaAnesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.
Chinwe AnumuduAnesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.
Jeremy ArmbrusterAnesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.
Maxwell JollyAnesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.
Justin MaginAnesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.
Gisselle MaquoitAnesthesiology, Duke University School of Medicine, Durham, USA.
Stuart A GrantAnesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis cadaveric dye study assesses the effect of volume and number of injections on the spread of solution after ultrasound-guided rectus sheath injections. In addition, this study evaluates the impact of the arcuate line on solution spread. MATERIALS AND

methodsUltrasound-guided rectus sheath injections were performed on seven cadavers on both sides of the abdomen, for a total of 14 injections. Three cadavers received one injection of 30 mL of a solution consisting of bupivacaine and methylene blue at the level of the umbilicus. Four cadavers received two injections of 15 mL of the same solution, one midway between the xiphoid process and umbilicus and one midway between the umbilicus and pubis.

resultsSix cadavers were successfully dissected and analyzed for a total of 12 injections, while one cadaver was excluded due to poor tissue quality that was inadequate for dissection and analysis. There was a significant spread of solution with all injections caudally to the pubis without limitation by the arcuate line. However, a single 30 mL injection showed inconsistent spread to the subcostal margin in four of six injections, including in a cadaver with an ostomy. A double injection of 15 mL showed consistent spread from xiphoid to pubis in five of six injections, except in a cadaver with a hernia.

conclusionsInjections deep to the rectus abdominis muscle, using the same technique as an ultrasound-guided rectus sheath block, achieve spread along a large and continuous fascial plane without limitation by the arcuate line and may provide coverage of the entire anterior abdomen. A large volume is necessary for complete coverage and spread is improved with multiple injections. We suggest that two injections with a total volume of at least 30 mL per side may be needed to achieve adequate coverage in the absence of preexisting abdominal abnormalities.

Indexed as

cadaver dissectionchronic and acute pain managementrectus sheath blockregional anesthesia and chronic painultra sound guided nerve block

Identifiers

PMID36843817
PMCPMC9949744

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.