Evidence map›Paper›PMID 36843417›Full record

ArticleAddiction (Abingdon, England)2023

Financial incentives for quitting smoking in pregnancy: Are they cost-effective?

Nicola McMeekin, Lesley Sinclair, Lyn Robinson-Smith, Alex Mitchell, Linda Bauld, David M Tappin, Kathleen A Boyd

Abstract readEvaluation Study
In one paragraph

Article in Addiction (Abingdon, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Incentives for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicola McMeekinHealth Economics and Health Technology Assessment, Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.ORCID 0000-0003-2918-8820
Lesley SinclairYork Trials Unit, Department of Health Sciences, Faculty of Science, University of York, YO10 5DD, York, UK.
Lyn Robinson-SmithYork Trials Unit, Department of Health Sciences, Faculty of Science, University of York, YO10 5DD, York, UK.
Alex MitchellYork Trials Unit, Department of Health Sciences, Faculty of Science, University of York, YO10 5DD, York, UK.
Linda BauldUsher Institute and SPECTRUM Consortium, University of Edinburgh, Edinburgh, EH8 9AG, UK.
David M TappinChild Health, School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.
Kathleen A BoydHealth Economics and Health Technology Assessment, Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.

Funding

Cancer Research UK 29792Cancer Research UK C48006/A20863Chief Scientist Office HIPS/16/01Medical Research Council MR/S037519/1
6 · The paper itself

Abstract

aimsTo evaluate whether adding financial incentives to usual care is cost-effective in encouraging pregnant women to quit tobacco smoking, compared with usual care alone.

designCost-effectiveness analysis (CEA) and cost-utility analysis (CUA) from a health-care provider's perspective, embedded in the Smoking Cessation in Pregnancy Incentives Trial (CPIT III). Long-term analyses were conducted from the same perspective, using an existing Markov model over a life-time horizon.

settingSeven maternity smoking cessation sites in Scotland, England and Northern Ireland in the United Kingdom.

participantsIn the short-term analysis, CPIT III participants were assessed: women 16 years or older, self-reporting as smokers, fewer than 24 weeks pregnant and English-speaking (n = 944). The same population was used for the life-time analysis, plus their infants. MEASUREMENTS: Costs included financial incentive vouchers and postage, cessation support and nicotine replacement therapy and neonatal stays. The outcome measure was a biochemically verified quit rate for the CEA and quality-adjusted life-years (QALYs) for CUA. Costs are presented in 2020 GBP sterling (£). Data for the life-time analysis came from the trial and were combined with data from published literature embedded in the model, reporting incremental cost per quitter and QALY. A 3.5% discount rate was applied.

findingsThe short-term incremental cost per quitter was £4400 and cost per QALY was £150 000. Results of sensitivity analyses confirmed these results. The long-term analysis combined costs and outcomes for mother and infants; results showed a cost saving of £37 [95% confidence interval (CI]) = £35-106] and increase in QALYs of 0.171 (95% CI = 0.124-0.229). These findings indicate that, over a life-time, financial incentives are cost-saving and improve health outcomes.

conclusionsIn the United Kingdom, offering up to £400 financial incentives, in addition to usual care, to support pregnant women to stop smoking appears to be highly cost-effective over a life-time for mother and infants.

Indexed as

Smoking CessationCost-Benefit AnalysisFemaleHumansInfant, NewbornMotivationPregnancySmokingTobacco SmokingTobacco Use Cessation DevicesChild healthcost-effectiveness analysiseconomic evaluationfinancial incentivespregnancysmoking cessation

Identifiers

PMID36843417
PMCPMC10952957

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.