Evidence map›Paper›PMID 36843270›Full record

ArticleAnalytical chemistry2023

Two-Dimensional Fe-N-C Single-Atomic-Site Catalysts with Boosted Peroxidase-Like Activity for a Sensitive Immunoassay.

Zhaoyuan Lyu, Shichao Ding, Lingzhe Fang, Xin Li, Tao Li, Mingjie Xu, Xiaoqing Pan, Wenlei Zhu, Yang Zhou, Dan Du and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhaoyuan LyuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.ORCID 0000-0003-0888-8297
Shichao DingSchool of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.ORCID 0000-0003-3795-306X
Lingzhe FangDepartment of Chemistry and Biochemistry, Northern Illinois University, DeKalb, Illinois 60115, United States.
Xin LiSchool of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.
Tao LiDepartment of Chemistry and Biochemistry, Northern Illinois University, DeKalb, Illinois 60115, United States.ORCID 0000-0002-4913-4486
Mingjie XuIrvine Materials Research Institute (IMRI), University of California, Irvine, California 92697, United States.
Xiaoqing PanIrvine Materials Research Institute (IMRI), University of California, Irvine, California 92697, United States.ORCID 0000-0002-0965-8568
Wenlei ZhuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.ORCID 0000-0001-6110-993X
Yang ZhouSchool of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.
Dan DuDL ADV-Tech, Pullman, Washington 99163, United States.ORCID 0000-0003-1952-4042
Yuehe LinSchool of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.ORCID 0000-0003-3791-7587

Funding

Single-Atom Nanozyme Enhanced Handheld Biosensor for Measurement of Pesticide ExposuresR43ES031885 · NIEHS · DL ADV-TECH, LLC · PI LI, SUIQIONG · 2020 to 2020
$147k
NIEHS NIH HHS R43 ES031885
6 · The paper itself

Abstract

Single-atomic-site catalysts (SASCs) with peroxidase (POD)-like activities have been widely used in various sensing platforms, like the enzyme-linked immunosorbent assay (ELISA). Herein, a two-dimensional Fe-N-C-based SASC (2D Fe-SASC) is successfully synthesized with excellent POD-like activity (specific activity = 90.11 U/mg) and is used to design the ELISA for herbicide detection. The 2D structure of Fe-SASC enables the exposure of numerous single atomic active sites on the surface as well as boosts the POD-like activity, thereby enhancing the sensing performance. 2D Fe-SASC is assembled into competitive ELISA kit, which achieves an excellent detection performance for 2,4-dichlorophenoxyacetic acid (2,4-D). Fe-SASC has great potential in replacing high-cost natural enzymes and working on various advanced sensing platforms with high sensitivity for the detection of various target biomarkers.

Indexed as

HerbicidesPeroxidaseEnzyme-Linked Immunosorbent AssayImmunoassayHerbicidesPeroxidase

Identifiers

PMID36843270
PMCPMC11993318

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.