Evidence map›Paper›PMID 36843202›Full record

ReviewJournal of clinical laboratory analysis2023

Diagnostic challenges of renal medullary carcinoma and the role for cytologic assessment: Case report and literature review.

Benjamin O Severseike, Kristian T Schafernak, Scott D Willard, Luis F Goncalves, Alok K Kothari, Francis K Eshun, Ross Mangum

Open access · goldFull text readReviewCase Reports
In one paragraph

Review in Journal of clinical laboratory analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Benjamin O SeverseikePhoenix Children's Hospital Residency Program Alliance (PCHRP), Phoenix Children's Hospital, Phoenix, Arizona, USA.
Kristian T SchafernakPathology and Laboratory Medicine, Phoenix Children's Hospital, Phoenix, Arizona, USA.
Scott D WillardDepartment of Child Health, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Luis F GoncalvesDepartment of Child Health, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Alok K KothariDepartment of Child Health, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Francis K EshunDepartment of Child Health, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Ross MangumDepartment of Child Health, University of Arizona College of Medicine, Phoenix, Arizona, USA.ORCID https://orcid.org/0000-0002-2288-042X
Creighton University · USPhoenix Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal medullary carcinoma (RMC) is a diagnostically challenging, aggressive primary renal malignancy associated with abysmal survival. Delays in diagnosis contribute to most patients having diffusely metastatic disease at the time of initial presentation.

methodsWe present the case of a 13-year-old African American male with sickle cell trait who presented with a renal mass and hematuria. Evaluation included imaging, fluid cultures, and cytologic assessment.

resultsPatient was diagnosed with RMC based on cytologic assessment of sub-centimeter fluid collections aspirated from the left kidney at the time of cortical biopsy for suspected renal mass. The additional fluid aspiration in conjunction with renal biopsy was an atypical but crucial step in early diagnosis.

conclusionCytomorphologic evaluation of fluid biospecimens is not currently part of the standard work-up for patients with renal masses but, when available, can provide crucial information that reduces time to diagnosis. Prompt symptom recognition and treatment initiation may improve patient outcomes.

Indexed as

Carcinoma, MedullaryCarcinoma, Renal CellKidney NeoplasmsAdolescentBiopsyHumansKidneyMalefine-needle aspirationpediatricsrenal medullary carcinomasickle cell traitSMARCB1 (INI)

Identifiers

PMID36843202
PMCPMC10020844
OpenAlexW4322194761

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read16
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.