ArticleJournal of translational medicine2023
Muscle distribution in relation to all-cause and cause-specific mortality in young and middle-aged adults.
Article in Journal of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Low lean mass and all-cause mortality risk in the middle-aged and older population: a dose-response meta-analysis of prospective cohort studies.Frontiers in medicine · 2025Pooled it
- Association between android-to-gynoid lean mass ratio and advanced cardiovascular-kidney-metabolic syndrome, and the cross-sectional association decomposition of estimated glucose disposal rate.Clinics (Sao Paulo, Brazil) · 2026Article
- Body mass index, waist circumference and the association with all-cause and cause-specific mortality: a 7.2-year follow-up cohort study in Shanghai, China.BMC public health · 2025Article
- Non-linear association between extracellular water/total body water ratio and all-cause mortality: a population-based cohort study.Scientific reports · 2025Article
- The Critical Role of Body Composition Assessment in Advancing Research and Clinical Health Risk Assessment across the Lifespan.Journal of obesity & metabolic syndrome · 2025Review
- Prognostic value of combined NP and LHb index with absolute monocyte count in colorectal cancer patients.Scientific reports · 2025Article
- Article
- Impact of dietary antioxidants on female infertility risk: evidence from NHANES.Scientific reports · 2024Article
- Association of weight-adjusted waist index with all-cause mortality among non-Asian individuals: a national population-based cohort study.Nutrition journal · 2024Article
- Central Lean Mass Distribution and the Risks of All-Cause and Cause-Specific Mortality in 40,283 UK Biobank Participants.Obesity facts · 2024Article
- Predicted lean body mass trajectories, and cancer risk and cancer-specific and all-cause mortality: A prospective cohort study.Journal of cachexia, sarcopenia and muscle · 2023Article
- Relationship between Composite Dietary Antioxidant Index and Aging.Healthcare (Basel, Switzerland) · 2023Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between muscle and prognosis, especially that between muscle distribution across different body parts, and the related prognosis is not well established.
objectiveTo investigate the relationship between muscle distribution and all-cause and cause-specific mortality and their potential modifiers.
designLongitudinal cohort study. C-index, IDI, and NRI were used to determine the best indicator of prognosis. COX regression analysis was performed to explore the relationship between variables and outcomes. Interaction and subgroup analyses were applied to identify the potential modifiers.
participantsA total of 5052 participants (weighted: 124,841,420) extracted from the NHANES 2003-2006 of median age 45 years and constituting 50.3% men were assessed. For validation, we included 3040 patients from the INSCOC cohort in China. MAIN MEASURES: Muscle mass and distribution. KEY
resultsCOX regression analysis revealed that upper limbs (HR = 0.41, 95% CI 0.33-0.51), lower limbs (HR = 0.54, 95% CI 0.47-0.64), trunk (HR = 0.71, 95% CI, 0.59-0.85), gynoid (HR = 0.47, 95% CI 0.38-0.58), and total lean mass (HR = 0.55, 95% CI 0.45-0.66) were all associated with the better survival of participants (P
conclusionMuscle mass and its distribution affect the prognosis with a more significant impact on the near-term than that on the long-term prognosis. Age and sex acted as vital modifiers.
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