Evidence map›Paper›PMID 36841763›Full record

ArticleHarm reduction journal2023

Racial/ethnic disparities in opioid overdose prevention: comparison of the naloxone care cascade in White, Latinx, and Black people who use opioids in New York City.

Maria R Khan, Lee Hoff, Luther Elliott, Joy D Scheidell, John R Pamplin, Tarlise N Townsend, Natalia M Irvine, Alex S Bennett

Open access · goldAbstract read
In one paragraph

Article in Harm reduction journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
27.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.

  1. Pooled it
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  5. Correlates of Rural Naloxone Possession Among People Who Use Drugs: A Multi-State Cross-Sectional Analysis.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026
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  9. The Experiences and Attitudes of Rural Black People who Use Drugs.Journal of racial and ethnic health disparities · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Maria R KhanDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, USA. maria.khan@nyulangone.org.
Lee HoffDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, USA.
Luther ElliottCenter for Drug Use and HIV/HCV Research, New York University School of Global Public Health, New York, NY, USA.
Joy D ScheidellDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, USA.
John R PamplinCenter for Opioid Epidemiology and Policy, New York University Grossman School of Medicine, New York, NY, USA.
Tarlise N TownsendDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, USA.
Natalia M IrvineDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, USA.
Alex S BennettCenter for Drug Use and HIV/HCV Research, New York University School of Global Public Health, New York, NY, USA.
New York University · USColumbia University · USNew York College of Health Professions · US

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan · 1998 to 2026
$38.9M
New York University, City University of New York Health Promotion & Prevention ReU48DP005008 · DP · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI THORPE, LORNA, TRINH-SHEVRIN, CHAU · 2014 to 2018
$6.9M
Overdose Risk Management and Compensation in the Era of NaloxoneR01DA046653 · NIDA · NEW YORK UNIVERSITY · PI BENNETT, ALEXANDER S, ELLIOTT, LUTHER · 2018 to 2022
$4.4M
NCCDPHP CDC HHS U48 DP005008NIDA NIH HHS P30 DA011041NIDA NIH HHS R01 DA046653
6 · The paper itself

Abstract

backgroundDrug overdose mortality is rising precipitously among Black people who use drugs. In NYC, the overdose mortality rate is now highest in Black (38.2 per 100,000) followed by the Latinx (33.6 per 100,000) and white (32.7 per 100,000) residents. Improved understanding of access to harm reduction including naloxone across racial/ethnic groups is warranted.

methodsUsing data from an ongoing study of people who use illicit opioids in NYC (N = 575), we quantified racial/ethnic differences in the naloxone care cascade.

resultsWe observed gaps across the cascade overall in the cohort, including in naloxone training (66%), current possession (53%) daily access during using and non-using days (21%), 100% access during opioid use (20%), and complete protection (having naloxone and someone who could administer it present during 100% of opioid use events; 12%). Naloxone coverage was greater in white (training: 79%, possession: 62%, daily access: 33%, access during use: 27%, and complete protection: 13%, respectively) and Latinx (training: 67%, possession: 54%, daily access: 22%, access during use: 24%, and complete protection: 16%, respectively) versus Black (training: 59%, possession: 48%, daily access:13%, access during use: 12%, and complete protection: 8%, respectively) participants. Black participants, versus white participants, had disproportionately low odds of naloxone training (OR 0.40, 95% CI 0.22-0.72). Among participants aged 51 years or older, Black race (versus white, the referent) was strongly associated with lower levels of being trained in naloxone use (OR 0.20, 95% CI 0.07-0.63) and having 100% naloxone access during use (OR 0.34, 95% CI 0.13-0.91). Compared to white women, Black women had 0.27 times the odds of being trained in naloxone use (95% CI 0.10-0.72).

conclusionsThere is insufficient protection by naloxone during opioid use, with disproportionately low access among Black people who use drugs, and a heightened disparity among older Black people and Black women.

Indexed as

Drug OverdoseOpiate OverdoseOpioid-Related DisordersAnalgesics, OpioidBlack or African AmericanBlack PeopleFemaleHispanic or LatinoHumansNaloxoneNew York CityWhiteAnalgesics, OpioidNaloxoneNaloxone carePreventionRacial/ethnic disparities

Identifiers

PMID36841763
PMCPMC9959933
OpenAlexW4322009723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.