Evidence map›Paper›PMID 36841759›Full record

ArticleBMC ophthalmology2023

Clinic study on macular epiretinal membrane in patients under the age of 40 years.

Nan Wang, Aohua Peng, Shengguo Li, Chun Ding

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Observational
  2. Anatomical, Functional, and Prognostic Results of Vitrectomy in Epiretinal Membranes Secondary to Retinal Vein Occlusions.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2025
    Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Nan WangDepartment of Ophthalmology, the Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Changsha, 410011, China.
Aohua PengDepartment of Ophthalmology, the Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Changsha, 410011, China.
Shengguo LiDepartment of Ophthalmology, Changsha Aier Eye Hospital, Changsha, China.
Chun DingDepartment of Ophthalmology, the Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Changsha, 410011, China. chunding@csu.edu.cn.
Central South University · CNHe Eye Hospital · CNSecond Xiangya Hospital of Central South University · CN

Funding

Development Project of Hunan Development and Reform Commission (No. 2021-212)Scientific Research Project of Hunan Provincial Health Commission No. C202307027337Scientific Research Project of Hunan Provincial Health Commission No. D202307028349
6 · The paper itself

Abstract

backgroundTo describe the risk factors and clinical characteristics of macular epiretinal membrane (MEM) disease in patients up to the age of 40 years and to evaluate the therapeutic effect of IVTA on MEM.

methodsClinical records were reviewed and the etiology of each case and the age distribution data were collected in this retrospective, cohort study. The clinical characteristics of MEM and the factors affecting VA were analyzed. Additionally, we contrasted the effects of MEM peeling with and without intravitreal triamcinolone acetonide on visual acuity (VA) and central foveal thickness (CFT).

resultsIn young patients, the incidence of partial posterior vitreous detachment (P-PVD) was considerably higher in IMEM than SMEM (P = 0.007). Furthermore, patients with stage 3 MEM had lower BCVA values than patients with stage 4 MEM (P < 0.001). Patients who live in urban had lower BCVA values than patients in rural (P < 0.001). Patients with IS/OS integrity had lower BCVA values than patients without IS/OS integrity (P < 0.001). The BCVA values in patients with IMEM were significantly lower than those of patients with SMEM (P < 0.001). BCVA was associated most commonly with etiology (P = 0.001), followed by region (P = 0.002). All patients had a decrease in logMAR Vas and CFT, but the combination of intraoperative IVTA resulted in a more significant decrease in logMAR Vas (P = 0.007) and CFT (P = 0.046).

conclusionIn young patients, the incidence of P-PVD was significantly higher in IMEM cases than in SMEM cases. The region, MEM stage, IS/OS integrity, and etiology influenced VA. Etiology was associated most commonly with BCVA. In individuals under 40, the combination of intraoperative IVTA resulted in a more significant decrease in logMAR Vas and CFT.

Indexed as

Epiretinal MembraneAdultCohort StudiesGlucocorticoidsHumansRetrospective StudiesTomography, Optical CoherenceTreatment OutcomeTriamcinolone AcetonideGlucocorticoidsTriamcinolone AcetonideCentral foveal thicknessInner segment/outer segmentIntravitreal triamcinolone acetonideMacular epiretinal membranePosterior vitreous detachmentVisual acuity

Identifiers

PMID36841759
PMCPMC9960427
OpenAlexW4322008073

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.