SynthesisEpigenetics2023
Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis.
Open access · diamondAbstract readMeta-Analysis
In one paragraph
Synthesis in Epigenetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Handling of multicohort data in pooled analysis of environmental exposures: confounding by cohort of the relationship between perfluoroalkyl substances and birthweight in the ECHO Program.American journal of epidemiology · 2026Article
- Diminished Maternal Tryptophan Leads to Sexually Dimorphic Differences in the Placenta-Brain Axis.Nutrients · 2026Article
- Sex-influenced DNA methylation differs by placental cell type.Biology of sex differences · 2026Article
- Placental DNA methylation dysregulation underlies fetal growth restriction associated with maternal pre-pregnancy underweight.BMC pregnancy and childbirth · 2026Article
- Article
- Epigenetic mechanisms linking the perinatal environment, the placenta, and maternal and child health outcomes: evidence for sexual dimorphism.Environmental epigenetics · 2026Article
- Placental DNA methylation key topics: sex- and cell-type specificity, mediation, multi-omics, and biomarker discovery.Epigenomics · 2025Review
- The association of prenatal ambient air pollution with placental epigenetic gestational age at birth.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Article
- Sexually dimorphic DNA methylation and gene expression patterns in human first trimester placenta.Biology of sex differences · 2024Article
- Bridging Differences in Cohort Analyses of the Relationship between Secondhand Smoke Exposure during Pregnancy and Birth Weight: The Transportability Framework in the ECHO Program.Environmental health perspectives · 2024Article
- Sex-based disparities in DNA methylation and gene expression in late-gestation mouse placentas.Biology of sex differences · 2024Article
- The role of DNA methylation in placental development and its implications for preeclampsia.Frontiers in cell and developmental biology · 2024Review
- Differential impact of prenatal PTSD symptoms and preconception trauma exposure on placentalStress (Amsterdam, Netherlands) · 2024Article
- CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns.Cell communication and signaling : CCS · 2023Article
- The application of epiphenotyping approaches to DNA methylation array studies of the human placenta.Epigenetics & chromatin · 2023Article
- The application of epiphenotyping approaches to DNA methylation array studies of the human placenta.Research square · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 7 institutions in 1 country.
Catherine M BulkaDepartment of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Todd M EversonGangarosa Department of Environmental Health, Emory University Rollins School of Public Health, Atlanta, GA, USA.
Amber A BurtGangarosa Department of Environmental Health, Emory University Rollins School of Public Health, Atlanta, GA, USA.
Carmen J MarsitGangarosa Department of Environmental Health, Emory University Rollins School of Public Health, Atlanta, GA, USA.
Margaret R KaragasDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Kristen E BoyleSection of Nutrition, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Sierra NiemiecColorado School of Public Health, The Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Aurora, CO, USA.
Katerina KechrisColorado School of Public Health, The Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Aurora, CO, USA.
Elizabeth J DavidsonDepartment of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Ivana V YangColorado School of Public Health, The Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Aurora, CO, USA.
Jason I FeinbergDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, ML, USA.
Heather E VolkDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, ML, USA.
Christine Ladd-AcostaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, ML, USA.
Carrie V BretonDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA.
T Michael O'SheaDepartment of Pediatrics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Rebecca C FryDepartment of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0003-0899-9018
program collaborators for Environmental influences on Child Health Outcomes
Colorado School of Public Health · USEmory University · USJohns Hopkins University · USUniversity of North Carolina at Chapel Hill · USDartmouth College · USUniversity of Colorado Denver · USUniversity of Southern California · US
Funding
Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI Phillip Brian Smith · 2016 to 2026
$215.9MECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4MVARIATION IN BIOACCUMULATION AND BIOMAGNIFICATION OF METALS IN NORTHERN US LAKESP42ES007373 · NIEHS · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA · 1995 to 2019
$52.0MColorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0MA prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3MThe ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7MUNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3MPILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS · 1995 to 2026
$32.6MLifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory Health (LA DREAMERs)UH3OD023287 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M, BRETON, CARRIE VAN DOREN · 2018 to 2022
$28.4MPilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6MThe Role of the Placenta-Brain Axis in Children's NeurodevelopmentUH3OD023348 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Rebecca Fry, Michael O'SHEA · 2018 to 2026
$21.9MENVIRONMENTAL INFLUENCES ON NEURODEVELOPMENTAL OUTCOME IN INFANTS BORN VERY PRETERMUH3OD023347 · OD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI LESTER, BARRY M., MARSIT, CARMEN JOSEPH · 2018 to 2022
$18.4MNCATS NIH HHS UL1 TR001082NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK076648NIEHS NIH HHS P01 ES022832NIEHS NIH HHS P30 ES010126NIEHS NIH HHS P30 ES019776NIEHS NIH HHS P42 ES007373NIEHS NIH HHS U24 ES028507NIH HHS U24 OD023319NIH HHS U24 OD023382NIH HHS U2C OD023375NIH HHS UG3 OD023248NIH HHS UH3 OD023275NIH HHS UH3 OD023287NIH HHS UH3 OD023342NIH HHS UH3 OD023347NIH HHS UH3 OD023348
Abstract
The placenta undergoes many changes throughout gestation to support the evolving needs of the foetus. There is also a growing appreciation that male and female foetuses develop differently
Indexed as
DNA MethylationPlacentaChildEpigenesis, GeneticFemaleGestational AgeHumansInfantMalePregnancySex CharacteristicsDNA methylationgestational agePlacentasex differences
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.