Evidence map›Paper›PMID 36840946›Full record

ArticleEpigenetics2023

CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis.

Xiyu Dai, Xinan Chen, Wensun Chen, Yuxi Ou, Yiling Chen, Siqi Wu, Quan Zhou, Chen Yang, Limin Zhang, Haowen Jiang

Abstract read
In one paragraph

Article in Epigenetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Circular RNAs and Cancers.Advances in experimental medicine and biology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Role of Circular RNAs in Prostate Cancer.Current medicinal chemistry · 2024
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiyu DaiDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Xinan ChenDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Wensun ChenDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Yuxi OuDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Yiling ChenDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Siqi WuDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Quan ZhouDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Chen YangDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Limin ZhangDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Haowen JiangDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the most prevalent type of cancer among men worldwide. The importance of circular RNA (circRNA) in prostate cancer and its connection to malignancy has been steadily recognized. circRNA expression was obtained by circRNA sequencing of prostate cancer. circRNA and its function were further analysed. The results were verified by qRT-PCR, RIP assay, FISH, RNA pulldown, WB, CCK-8, colony formation assay and wound-healing assay. BALB/c Nude mice were used for xenograft hosts. Low expression of circDHRS3 was assessed in prostate cancer. Overexpression of circDHRS3 inhibited prostate cancer growth and migration

Indexed as

Homeodomain ProteinsMicroRNAsProstatic NeoplasmsRNA, CircularTranscription FactorsAlcohol OxidoreductasesAnimalsCell Line, TumorCell MovementCell ProliferationDNA MethylationGene Expression Regulation, NeoplasticHumansIn Situ Hybridization, FluorescenceMaleMiceAlcohol OxidoreductasesHomeodomain ProteinsMEIS2 protein, humanMicroRNAsMIRN421 microRNA, humanRNA, CircularTranscription FactorscircDHRS3circRNAMEIS2prostate cancer

Identifiers

PMID36840946
PMCPMC9980676

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.