Evidence map›Paper›PMID 36840794›Full record

ReviewMolecular genetics and genomics : MGG2023

Strategic transgene-free approaches of CRISPR-based genome editing in plants.

Sougata Bhattacharjee, Rakesh Bhowmick, Lakshmi Kant, Krishnayan Paul

Abstract readReview
In one paragraph

Review in Molecular genetics and genomics : MGG, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  11. Substantial enhancement ofHorticulture research · 2025
    Article
  12. Review
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  14. Article
  15. Optimization of a CRISPR-Cas9Frontiers in plant science · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sougata BhattacharjeeSchool of Crop Science, ICAR-Indian Agricultural Research Institute, Jharkhand, 825405, India. sougata.b@icar.gov.in.ORCID http://orcid.org/0000-0002-8037-3127
Rakesh BhowmickCrop Improvement Division, ICAR-VPKAS, Almora, 263601, India.
Lakshmi KantCrop Improvement Division, ICAR-VPKAS, Almora, 263601, India.
Krishnayan PaulNational Institute for Plant Biotechnology, New Delhi, 110012, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome editing through the alteration of nucleotide sequence has already revolutionized the field of site-directed mutagenesis for a decade. However, research in terms of precision and efficacy in targeting the loci and reduction in off-target mutation has always been a priority when DNA is involved. Therefore, recent research interest lies in utilizing the same precision technology but results in non-transgenic. In this review article, different technological advancements have been explained, which may provide a holistic concept of and need for transgene-free genome editing. The advantage and lacunas of each technology have been critically discussed to deliver a transparent view to the readers. A systematic analysis and evaluation of published research articles implied that researchers across the globe are putting continuous efforts in this direction to eliminate the hindrance of transgenic regulation. Nevertheless, this approach has severe implications legitimate for mitigating the conflict of acceptance, reliability, and generosity of gene-editing technology and sustainably retorting to the expanding global population feeding challenges.

Indexed as

CRISPR-Cas SystemsGene EditingDNAGenome, PlantPlantsPlants, Genetically ModifiedReproducibility of ResultsDNABase editingCRISPR/CasDNA freeGene editingNon-genetically modified organisms (GMO)Ribonucleoprotein complexTransgene free

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.