Evidence map›Paper›PMID 36840540›Full record

ArticleSchizophrenia bulletin2023

Recreational Drug Use and Distress From Hallucinations in the General Dutch Population.

Monique van der Weijden-Germann, Sanne G Brederoo, Mascha M J Linszen, Iris E C Sommer

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Monique van der Weijden-GermannDepartment of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen (UMCG), Groningen, The Netherlands.
Sanne G BrederooDepartment of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen (UMCG), Groningen, The Netherlands.
Mascha M J LinszenDepartment of Psychiatry and Brain Center Rudolf Magnus, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands.
Iris E C SommerDepartment of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen (UMCG), Groningen, The Netherlands.

Funding

ZonMw Mental Health 63631 001 0
6 · The paper itself

Abstract

background and hypothesisDistress associated with auditory (AH) and visual (VH) hallucinations in the general population was found to be predictive of later need for mental healthcare. It is, therefore, important to understand factors relating to the distress individuals experience from their hallucinations. Hallucinations can easily occur under substance-induced states, but recreational drug use is also known as a self-medication strategy. The current study, therefore, investigated whether recreational drug use by individuals from the general population is associated with the degree of distress experienced from AH and/or VH. STUDY

designDrug use and distress severity associated with AH (N = 3.041) and/or VH (N = 2.218) were assessed by means of an online survey in the general Dutch population (>14 years of age). STUDY

resultsMultiple linear regression revealed that while past month consumption of alcohol was associated with less AH- and VH-related distress, past month cannabis use was associated with more AH- and VH-related distress. Furthermore, past month use of nitrous oxide was associated with more severe VH-related distress.

conclusionRecreational use of alcohol, cannabis, and nitrous oxide may play important differential roles in the degree of distress associated with AH and VH in individuals from the general population. The consumption of these substances could form a potential risk factor for the development of distressing hallucinations or function as a signal marker for their occurrence. Due to the cross-sectional design of the current study, the causal relation between recreational drug use and distressing hallucinations remains to be elucidated.

Indexed as

Nitrous OxideRecreational Drug UseCross-Sectional StudiesHallucinationsHumansNitrous Oxidealcoholcannabishallucinatory distressnitrous oxiderecreational drug useschizophrenia

Identifiers

PMID36840540
PMCPMC9960006

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.