Evidence map›Paper›PMID 36840024›Full record

ReviewPharmaceutics2023

Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems.

Monu Kumar Shukla, Harshita Tiwari, Rachna Verma, Wen-Liang Dong, Shavkatjon Azizov, Brajesh Kumar, Sadanand Pandey, Deepak Kumar

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Monu Kumar ShuklaDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, India.ORCID 0000-0001-9758-0811
Harshita TiwariDiscovery Informatics Lab, Natural Products & Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Jammu 180001, India.
Rachna VermaDepartment of Basic Sciences, Shoolini University, Solan 173229, India.ORCID 0000-0001-5321-9450
Wen-Liang DongSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Shavkatjon AzizovLaboratory of Biological Active Macromolecular Systems, Institute of Bioorganic Chemistry, Academy of Sciences Uzbekistan, Tashkent 100125, Uzbekistan.ORCID 0000-0002-4978-8340
Brajesh KumarDepartment of Chemistry, TATA College, Kolhan University, Chaibasa 833202, India.ORCID 0000-0002-0557-9790
Sadanand PandeyDepartment of Chemistry, College of Natural Sciences, Yeungnam University, Gyeongsan 38541, Republic of Korea.ORCID 0000-0003-2065-897X
Deepak KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, India.ORCID 0000-0003-2241-0054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancements in the fields of ionic liquids (ILs) broaden its applications not only in traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids "Solutions for Your Success" have received a lot of interest from scientists due to a myriad of applications in the pharmaceutical industry for drug delivery systems as well as targeting different diseases. Solubility is a critical physicochemical property that determines the drug's fate at the target site. Many promising drug candidates fail in various phases of drug research due to poor solubility. In this context, ionic liquids are regarded as effective drug delivery systems for poorly soluble medicines. ILs are also able to combine different anions/cations with other cations/anions to produce salts that satisfy the concept behind the ILs. The important characteristics of ionic liquids are the modularity of their physicochemical properties depending on the application. The review highlights the recent advancement and further applications of ionic liquids to deliver drugs in the pharmaceutical and biomedical fields.

Indexed as

biological macromoleculesbiomedical applicationsdrug delivery systemsionic liquidswater solubility

Identifiers

PMID36840024
PMCPMC9963759

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.