Evidence map›Paper›PMID 36839823›Full record

ArticlePharmaceutics2023

Targeting Siderophore-Mediated Iron Uptake in

Matteo Mori, Giovanni Stelitano, Giulia Cazzaniga, Arianna Gelain, Andrea Tresoldi, Mario Cocorullo, Martina Roversi, Laurent R Chiarelli, Martina Tomaiuolo, Pietro Delre and 7 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Deferoxamine Exhibits Antimicrobial and Immunomodulatory Activity AgainstInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Targeting Siderophore Biosynthesis to Thwart Microbial Growth.International journal of molecular sciences · 2025
    Review
  7. International journal of molecular sciences · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Matteo MoriDepartment of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0002-7491-1494
Giovanni StelitanoDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Via A. Ferrata 9, 27100 Pavia, Italy.ORCID 0000-0002-5219-4770
Giulia CazzanigaDepartment of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0002-0942-8914
Arianna GelainDepartment of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0001-9104-732X
Andrea TresoldiDepartment of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy.
Mario CocorulloDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Via A. Ferrata 9, 27100 Pavia, Italy.ORCID 0000-0001-7074-0328
Martina RoversiDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Via A. Ferrata 9, 27100 Pavia, Italy.
Laurent R ChiarelliDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Via A. Ferrata 9, 27100 Pavia, Italy.ORCID 0000-0003-0348-9764
Martina TomaiuoloInstitute of Crystallography, National Research Council, Trieste Outstation, Area Science Park-Basovizza, S.S.14-Km. 163.5, 34149 Trieste, Italy.
Pietro DelreInstitute of Crystallography, National Research Council, Via G. Amendola 122/o, 70126 Bari, Italy.
Giuseppe F MangiatordiInstitute of Crystallography, National Research Council, Via G. Amendola 122/o, 70126 Bari, Italy.ORCID 0000-0003-4042-2841
Anna GriegoDepartment of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0003-4887-6645
Loris RizzelloDepartment of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0002-8230-853X
Alberto CassettaInstitute of Crystallography, National Research Council, Trieste Outstation, Area Science Park-Basovizza, S.S.14-Km. 163.5, 34149 Trieste, Italy.ORCID 0000-0002-8600-4162
Sonia CovaceuszachInstitute of Crystallography, National Research Council, Trieste Outstation, Area Science Park-Basovizza, S.S.14-Km. 163.5, 34149 Trieste, Italy.
Stefania VillaDepartment of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0002-0636-7589
Fiorella MeneghettiDepartment of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0002-6511-7360

Funding

Fondazione per la Ricerca sulla Fibrosi Cistica FFC#5/2022
6 · The paper itself

Abstract

Targeting pathogenic mechanisms, rather than essential processes, represents a very attractive approach for the development of new antimycobacterial drugs. In this context, iron acquisition routes have recently emerged as potentially druggable pathways. However, the importance of siderophore biosynthesis in the virulence and pathogenicity of

Indexed as

antimicrobial resistancecystic fibrosisdrug designgrating-coupled interferometry (GCI)homology modelsiderophores

Identifiers

PMID36839823
PMCPMC9966845

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.