Evidence map›Paper›PMID 36839795›Full record

ArticlePharmaceutics2023

Synergistic Combination of Irinotecan and Rapamycin Orally Delivered by Nanoemulsion for Enhancing Therapeutic Efficacy of Pancreatic Cancer.

Yu-Hsuan Liu, Ling-Chun Chen, Wen-Ting Cheng, Pu-Sheng Wei, Chien-Ming Hsieh, Ming-Thau Sheu, Shyr-Yi Lin, Hsiu-O Ho, Hong-Liang Lin

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu-Hsuan LiuSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
Ling-Chun ChenDepartment of Biotechnology and Pharmaceutical Technology, Yuanpei University of Medical Technology, Hsinchu 30015, Taiwan.
Wen-Ting ChengDepartment of Biotechnology and Pharmaceutical Technology, Yuanpei University of Medical Technology, Hsinchu 30015, Taiwan.
Pu-Sheng WeiSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
Chien-Ming HsiehSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-7204-4681
Ming-Thau SheuSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0003-1995-8369
Shyr-Yi LinDivision of Gastroenterology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.
Hsiu-O HoSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
Hong-Liang LinSchool of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

Funding

Jin-lung-yuan Foundation 2022-2023Ministry of Science and Technology of the Republic of China MOST 111-2221-E-037-004
6 · The paper itself

Abstract

In recent years, combining different types of therapy has emerged as an advanced strategy for cancer treatment. In these combination therapies, oral delivery of anticancer drugs is more convenient and compliant. This study developed an irinotecan/rapamycin-loaded oral lecithin-based self-nanoemulsifying nanoemulsion preconcentrate (

Indexed as

combination therapyirinotecanoral nano pharmaceuticalsrapamycinself-nanoemulsifying nanoemulsionsilymarin

Identifiers

PMID36839795
PMCPMC9963937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.