Evidence map›Paper›PMID 36839741›Full record

ArticlePharmaceutics2023

Microwave-Treated Physically Cross-Linked Sodium Alginate and Sodium Carboxymethyl Cellulose Blend Polymer Film for Open Incision Wound Healing in Diabetic Animals-A Novel Perspective for Skin Tissue Regeneration Application.

Saima Mahmood, Nauman Rahim Khan, Ghulam Razaque, Shefaat Ullah Shah, Memuna Ghafoor Shahid, Hassan A Albarqi, Abdulsalam A Alqahtani, Ali Alasiri, Hafiz Muhammad Basit

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Saima MahmoodGomal Centre for Pharmaceutical Sciences, Faculty of Pharmacy, Gomal University, DIKhan 29050, Khyber Pakhtunkhwa, Pakistan.
Nauman Rahim KhanGomal Centre for Pharmaceutical Sciences, Faculty of Pharmacy, Gomal University, DIKhan 29050, Khyber Pakhtunkhwa, Pakistan.ORCID 0000-0002-5698-3662
Ghulam RazaqueFaculty of Pharmacy, University of Baluchistan, Quetta 87300, Baluchistan, Pakistan.
Shefaat Ullah ShahGomal Centre for Pharmaceutical Sciences, Faculty of Pharmacy, Gomal University, DIKhan 29050, Khyber Pakhtunkhwa, Pakistan.ORCID 0000-0003-3271-2806
Memuna Ghafoor ShahidDepartment of Botany, Government College University, Lahore 54000, Punjab, Pakistan.
Hassan A AlbarqiDepartment of Pharmaceutics, College of Pharmacy, Najran University, Najran 55461, Saudi Arabia.ORCID 0000-0002-1902-2328
Abdulsalam A AlqahtaniDepartment of Pharmaceutics, College of Pharmacy, Najran University, Najran 55461, Saudi Arabia.ORCID 0000-0001-7243-8042
Ali AlasiriDepartment of Pharmaceutics, College of Pharmacy, Najran University, Najran 55461, Saudi Arabia.
Hafiz Muhammad BasitAkhtar Saeed College of Pharmacy, Bahria Golf City, Rawalpindi 46220, Punjab, Pakistan.
Gomal University · PKNajran University · SAGovernment College University, Lahore · PKUniversity of Balochistan · PK

Funding

Higher Education Commission 7493
6 · The paper itself

Abstract

This study aimed at developing the microwave-treated, physically cross-linked polymer blend film, optimizing the microwave treatment time, and testing for physicochemical attributes and wound healing potential in diabetic animals. Microwave-treated and untreated films were prepared by the solution casting method and characterized for various attributes required by a wound healing platform. The optimized formulation was tested for skin regeneration potential in the diabetes-induced open-incision animal model. The results indicated that the optimized polymer film formulation (MB-3) has significantly enhanced physicochemical properties such as high moisture adsorption (154.6 ± 4.23%), decreased the water vapor transmission rate (

Indexed as

cross-linkingdiabetes mellitusmicrowavepolymeric filmskin regenerationsodium alginatesodium carboxy methyl cellulosewound healing

Identifiers

PMID36839741
PMCPMC9959634
OpenAlexW4318480342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.