Evidence map›Paper›PMID 36839736›Full record

ArticlePharmaceutics2023

Preclinical Evaluation of a Lead Specific Chelator (PSC) Conjugated to Radiopeptides for

Mengshi Li, Nicholas J Baumhover, Dijie Liu, Brianna S Cagle, Frédéric Boschetti, Guillaume Paulin, Dongyoul Lee, Zhiming Dai, Ephraim R Obot, Brenna M Marks and 6 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 41 citations in OpenAlex.

  1. [European journal of nuclear medicine and molecular imaging · 2025
    Trial
  2. Article
  3. Review
  4. Review
  5. A Phase 0 Imaging Trial of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  6. Single Photon Emission Computed Tomography Tracer.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. EJNMMI radiopharmacy and chemistry · 2025
    Review
  14. Review
  15. DifferentToxics · 2025
    Article
  16. Article
  17. Review
  18. Side-by-Side Comparison of the In Vivo Performance of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  19. Article
  20. Lead-it-EAZY! GMP-compliant production of [EJNMMI radiopharmacy and chemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Mengshi LiViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.ORCID 0000-0003-3398-0183
Nicholas J BaumhoverViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.
Dijie LiuViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.
Brianna S CagleViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.
Frédéric BoschettiCheMatech-MDT, 21000 Dijon, France.
Guillaume PaulinCheMatech-MDT, 21000 Dijon, France.
Dongyoul LeeDepartment of Physics and Chemistry, Korea Military Academy, Seoul 01805, Republic of Korea.ORCID 0000-0002-4293-259X
Zhiming DaiDepartment of Chemistry, The University of Iowa, Iowa City, IA 52240, USA.
Ephraim R ObotViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.
Brenna M MarksViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.
Ibrahim OkeilViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.
Edwin A SagastumeViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.
Moustafa GabrDepartment of Radiology, Weill Cornell Medicine, New York, NY 10021, USA.ORCID 0000-0001-9074-3331
F Christopher PiggeDepartment of Chemistry, The University of Iowa, Iowa City, IA 52240, USA.ORCID 0000-0003-2700-7141
Frances L JohnsonViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.
Michael K SchultzViewpoint Molecular Targeting, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA.
Viewpoint Molecular Targeting (United States) · USUniversity of Iowa · USCornell University · USKorea Military Academy · KR

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Phase 1 cross over biodistribution study of [203Pb]VMT01 for single photon emission computed tomography (SPECT) and [68Ga]VMT02 for positron emission tomography (PET) imaging of stage 4 melanomaR44CA203430 · NCI · VIEWPOINT MOLECULAR TARGETING, INC. · PI JOHNSON, FRANCES L · 2019 to 2020
$2.0M
EARLY THERAPEUTICS DEVELOPMENT WITH PHASE 2 EMPHASIS-261017003N01CA017003 · NCI · UNIVERSITY OF TEXAS MD ANDERSON CAN CTR · 2002 to 2005
–
NCI NIH HHS N44CA170036; R44CA203430NCI NIH HHS P30 CA086862NCI NIH HHS R44 CA203430
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bismuth-212chelatorsLead-203Lead-212stabilitytheranostics

Identifiers

PMID36839736
PMCPMC9966725
OpenAlexW4318206217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.