Evidence map›Paper›PMID 36839714›Full record

ArticlePharmaceutics2023

Tuning the Molecular Structure of Corroles to Enhance the Antibacterial Photosensitizing Activity.

Edwin J Gonzalez Lopez, Sol R Martínez, Virginia Aiassa, Sofía C Santamarina, Rodrigo E Domínguez, Edgardo N Durantini, Daniel A Heredia

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Modulating the amphiphilic character of porphyrins with pH-activatable cationic centers and fluorocarbon chains to enhance antimicrobial photodynamic activity against Candida albicans.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Edwin J Gonzalez LopezIDAS-CONCIET-UNRC, Departamento de Química, Facultad de Ciencias Exactas Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Agencia Postal Nro. 3, Río Cuarto X5804BYA, Argentina.ORCID 0000-0002-4680-1087
Sol R MartínezIITEMA-CONICET, Departamento de Química, Facultad de Ciencias Exactas Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Agencia Postal Nro. 3, Río Cuarto X5804BYA, Argentina.
Virginia AiassaUNITEFA-CONICET, Departamento de Ciencias Farmacéuticas, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba X5000HUA, Argentina.
Sofía C SantamarinaIDAS-CONCIET-UNRC, Departamento de Química, Facultad de Ciencias Exactas Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Agencia Postal Nro. 3, Río Cuarto X5804BYA, Argentina.
Rodrigo E DomínguezINFIQC-CONICET, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba X5000HUA, Argentina.
Edgardo N DurantiniIDAS-CONCIET-UNRC, Departamento de Química, Facultad de Ciencias Exactas Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Agencia Postal Nro. 3, Río Cuarto X5804BYA, Argentina.ORCID 0000-0001-8901-7543
Daniel A HerediaIDAS-CONCIET-UNRC, Departamento de Química, Facultad de Ciencias Exactas Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Agencia Postal Nro. 3, Río Cuarto X5804BYA, Argentina.ORCID 0000-0002-0667-3906

Funding

Agencia Nacional de Promoción Científica y Tecnológica PICT-2019-02391National Scientific and Technical Research Council PIBAA 2022-2023, PIBAA 28720210101120CONational University of Río Cuarto SECYT-UNRC (PPI-2020 Res. 083/20).
6 · The paper itself

Abstract

The increase in the antibiotic resistance of bacteria is a serious threat to public health. Photodynamic inactivation (PDI) of micro-organisms is a reliable antimicrobial therapy to treat a broad spectrum of complex infections. The development of new photosensitizers with suitable properties is a key factor to consider in the optimization of this therapy. In this sense, four corroles were designed to study how the number of cationic centers can influence the efficacy of antibacterial photodynamic treatments. First, 5,10,15-Tris(pentafluorophenyl)corrole (

Indexed as

antimicrobialcorrolepH-activable cationic groupphotodynamic inactivationphotosensitizersreactive oxygen speciessuper bugs

Identifiers

PMID36839714
PMCPMC9959985

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.