Evidence map›Paper›PMID 36839684›Full record

ArticlePharmaceutics2023

Sericin/Human Placenta-Derived Extracellular Matrix Scaffolds for Cutaneous Wound Treatment-Preparation, Characterization,

Jayavardhini Bhoopathy, Sankari Dharmalingam, Weslen Vedakumari Sathyaraj, Selvarajan Rajendran, Shibormi Rymbai, Rethinam Senthil, Raji Atchudan

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Sericin Protein: Structure, Properties, and Applications.Journal of functional biomaterials · 2024
    Review
  4. Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Jayavardhini BhoopathyFaculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, Tamil Nadu, India.
Sankari DharmalingamDepartment of Biotechnology, College of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu, India.
Weslen Vedakumari SathyarajFaculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, Tamil Nadu, India.
Selvarajan RajendranCentre for Nano Science and Technology, Alagappa College of Technology Campus, Anna University, Chennai 600036, Tamil Nadu, India.
Shibormi RymbaiFaculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, Tamil Nadu, India.
Rethinam SenthilDepartment of Leather Engineering, Faculty of Engineering, Ege University, 35100 Izmir, Turkey.
Raji AtchudanSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.ORCID 0000-0001-8793-0953
Chettinad Academy of Research and Education · INAnna University, Chennai · INEge University · TRSRM Institute of Science and Technology · INYeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human placenta is loaded with an enormous amount of endogenous growth factors, thereby making it a superior biomaterial for tissue regeneration. Sericin is a naturally occurring silk protein that is extensively used for biomedical applications. In the present work, sericin and human placenta-derived extracellular matrix were blended and fabricated in the form of scaffolds using the freeze-drying method for cutaneous wound treatment. The prepared sericin/placenta-derived extracellular matrix (SPEM) scaffolds were characterized to determine their morphology, functional groups, mechanical strength, and antibacterial activity. Scanning electron microscopic analysis of the scaffolds showed smooth surfaces with interconnected pores.

Indexed as

decellularized extracellular matrixopen excision woundscaffoldssericin

Identifiers

PMID36839684
PMCPMC9962400
OpenAlexW4317735765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.