Evidence map›Paper›PMID 36839678›Full record

ArticlePharmaceutics2023

Half-Sandwich Rhodium Complexes with Releasable N-Donor Monodentate Ligands: Solution Chemical Properties and the Possibility for Acidosis Activation.

János P Mészáros, Wolfgang Kandioller, Gabriella Spengler, Alexander Prado-Roller, Bernhard K Keppler, Éva A Enyedy

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Characterization and biological evaluation of a Rh(III) complex featuring Phosphonate-Modified bipyridine ligands.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

János P MészárosMTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.ORCID 0000-0001-6301-5259
Wolfgang KandiollerInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Str. 42, A-1090 Vienna, Austria.ORCID 0000-0002-5630-712X
Gabriella SpenglerMTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.ORCID 0000-0001-8085-0950
Alexander Prado-RollerInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Str. 42, A-1090 Vienna, Austria.ORCID 0000-0002-3719-801X
Bernhard K KepplerInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Str. 42, A-1090 Vienna, Austria.
Éva A EnyedyMTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.ORCID 0000-0002-8058-8128
University of Szeged · HUUniversity of Vienna · AT

Funding

ELKH "Lendület" Programme, LP2019-6/2019National Research, Development and Innovation Office of Hungary TKP-2021-EGA-32
6 · The paper itself

Abstract

Cancer chemotherapeutics usually have serious side effects. Targeting the special properties of cancer and activation of the anticancer drug in the tumor microenvironment in situ may decrease the intensity of the side effects and improve the efficacy of therapy. In this study, half-sandwich Rh complexes are introduced, which may be activated at the acidic, extracellular pH of the tumor tissue. The synthesis and aqueous stability of mixed-ligand complexes with a general formula of [Rh(η

Indexed as

anticancerformation constantorganometallicpentamethylcyclopentadienylpiano-stool

Identifiers

PMID36839678
PMCPMC9964319
OpenAlexW4317734031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.