Evidence map›Paper›PMID 36839630›Full record

ArticlePharmaceutics2023

Heteroleptic Copper(II) Complexes Containing 2'-Hydroxy-4-(Dimethylamino)Chalcone Show Strong Antiproliferative Activity.

Zdeněk Trávníček, Tomáš Malina, Ján Vančo, Marek Šebela, Zdeněk Dvořák

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zdeněk TrávníčekRegional Center of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute (CATRIN), Palacký University, Šlechtitelů 241/27, CZ-783 71 Olomouc, Czech Republic.ORCID 0000-0002-5890-7874
Tomáš MalinaRegional Center of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute (CATRIN), Palacký University, Šlechtitelů 241/27, CZ-783 71 Olomouc, Czech Republic.ORCID 0000-0001-5631-607X
Ján VančoRegional Center of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute (CATRIN), Palacký University, Šlechtitelů 241/27, CZ-783 71 Olomouc, Czech Republic.ORCID 0000-0003-3351-1192
Marek ŠebelaDepartment of Biochemistry, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.ORCID 0000-0001-9835-1375
Zdeněk DvořákDepartment of Cell Biology and Genetics, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.ORCID 0000-0002-3938-3585
Regional Centre of Advanced Technologies and Materials · CZPalacký University Olomouc · CZ

Funding

Czech Science Foundation 21-19060SMinistry of Education Youth and Sports CZ.02.1.01/0.0/0.0/16_019/0000754
6 · The paper itself

Abstract

A series of six heteroleptic copper(II) complexes with 2'-hydroxy-4-(dimethylamino)chalcone (HL) with the composition [Cu(N-N)(L)]NO

Indexed as

antiproliferative activitycell cyclecell deathchalconecopper(II) complexesin vitro cytotoxicitymitochondrial membrane potentialreactive oxygen species

Identifiers

PMID36839630
PMCPMC9967299
OpenAlexW4317036530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.