Evidence map›Paper›PMID 36839573›Full record

ReviewPathogens (Basel, Switzerland)2023

Employing T-Cell Memory to Effectively Target SARS-CoV-2.

Zaw Htet Tun, Nang Thinn Thinn Htike, Chaw Kyi-Tha-Thu, Wing-Hin Lee

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Zaw Htet TunFaculty of Medicine, Royal College of Medicine Perak, Universiti Kuala Lumpur (UniKL RCMP), Ipoh 30450, Perak, Malaysia.ORCID 0000-0003-4225-8571
Nang Thinn Thinn HtikeFaculty of Medicine, Royal College of Medicine Perak, Universiti Kuala Lumpur (UniKL RCMP), Ipoh 30450, Perak, Malaysia.ORCID 0000-0001-5658-1826
Chaw Kyi-Tha-ThuDepartment of Immunology, Graduate School of Medicine, International University of Health and Welfare, Narita 286-8686, Japan.
Wing-Hin LeeFaculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur (UniKL RCMP), Ipoh 30450, Perak, Malaysia.
University of Kuala Lumpur · MYInternational University of Health and Welfare · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Well-trained T-cell immunity is needed for early viral containment, especially with the help of an ideal vaccine. Although most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected convalescent cases have recovered with the generation of virus-specific memory T cells, some cases have encountered T-cell abnormalities. The emergence of several mutant strains has even threatened the effectiveness of the T-cell immunity that was established with the first-generation vaccines. Currently, the development of next-generation vaccines involves trying several approaches to educate T-cell memory to trigger a broad and fast response that targets several viral proteins. As the shaping of T-cell immunity in its fast and efficient form becomes important, this review discusses several interesting vaccine approaches to effectively employ T-cell memory for efficient viral containment. In addition, some essential facts and future possible consequences of using current vaccines are also highlighted.

Indexed as

COVID-19lung TRMSARS-CoV-2T cellsvaccine

Identifiers

PMID36839573
PMCPMC9967959
OpenAlexW4320493498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.