ReviewNutrients2023
Iodine Deficiency and Iodine Prophylaxis: An Overview and Update.
Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fish consumption and cognitive function in aging: a systematic review of observational studies.GeroScience · 2026Pooled it
- Association between serum iodine and thyroid function in Malagasy adults: a cross-sectional study in a tertiary-level hospital in Antananarivo, Madagascar.The Libyan journal of medicine · 2026Article
- Roles of External Factors and Polygenic Susceptibility in Thyroid Nodules and Goiter Among Children Aged 8-10 Years in Iodine-adequate Areas of Northern China.Biological trace element research · 2026Article
- Effects of Iodine Nutritional Status on Thyroid Proliferation of SD Rat.Biological trace element research · 2026Article
- Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto's thyroiditis.Gland surgery · 2026Review
- Iodine in Health and Disease: A Comprehensive Review.Nutrients · 2026Review
- Iodine deficiency in the first pregnancy trimester and intelligence in adolescence.European journal of nutrition · 2026Article
- Iodine deficiency and excess in children and related factors in Alborz Province: a cross-sectional study.BMC nutrition · 2026Article
- Energy Allocation Resilience and Endocrine Integration.International journal of molecular sciences · 2026Review
- Influence of Heat Treatment Prior to Fortification on Goitrogenic Compounds, Iodine Stability and Antioxidant Activity in Cauliflower.Foods (Basel, Switzerland) · 2026Article
- Analysis of Determinants of Dietary Iodine Intake of Adolescents from Northern Regions of Poland: Coastal Areas and Lake Districts.Nutrients · 2025Article
- Reaffirming the role of iodine in cognitive health: a call for lifespan-based public health action.Annals of medicine and surgery (2012) · 2025Article
- Proficiency testing for urinary iodine and its impact on laboratory research related to iodine deficiency disorders (IDD) in the central Africa subregion.Thyroid research · 2025Article
- Household iodized salt consumption and iodine status in women of reproductive age in Angola: a cross-sectional study.Journal of health, population, and nutrition · 2025Observational
- Iodine Intake from Universal Salt Iodization Programs and Hashimoto's Thyroiditis: A Systematic Review.Diseases (Basel, Switzerland) · 2025Review
- A Scoping Review on the Prevalence of Hashimoto's Thyroiditis and the Possible Associated Factors.Medical sciences (Basel, Switzerland) · 2025Article
- Four-Dimensional Dual-Energy Computed Tomography-Derived Parameters and Their Correlation with Thyroid Gland Functional Status.Tomography (Ann Arbor, Mich.) · 2025Article
- Newborn screening for congenital hypothyroidism: worldwide coverage 50 years after its start.European thyroid journal · 2025Review
- Vegetarian Diets During Complementary Feeding: An Overview of Nutritional and Health Features.Children (Basel, Switzerland) · 2025Review
- Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The thyroid gland requires iodine to synthesize thyroid hormones, and iodine deficiency results in the inadequate production of thyroxine and related thyroid, metabolic, developmental, and reproductive disorders. Iodine requirements are higher in infants, children, and during pregnancy and lactation than in adult men and non-pregnant women. Iodine is available in a wide range of foods and water and is susceptible to almost complete gastric and duodenal absorption as an iodide ion. A healthy diet usually provides a daily iodine consumption not exceeding 50% of the recommended intake. Iodine supplementation is usually necessary to prevent iodine deficiency disorders (IDDs), especially in endemic areas. The community-based strategy of iodine fortification in salt has eradicated IDDs, such as endemic goiter and cretinism, in countries providing adequate measures of iodine prophylaxis over several decades in the 20th century. Iodized salt is the cornerstone of iodine prophylaxis in endemic areas, and the continuous monitoring of community iodine intake and its related clinical outcomes is essential. Despite the relevant improvement in clinical outcomes, subclinical iodine deficiency persists even in Western Europe, especially among girls and women, being an issue in certain physiological conditions, such as pregnancy and lactation, and in people consuming unbalanced vegetable-based or salt-restricted diets. Detailed strategies to implement iodine intake (supplementation) could be considered for specific population groups when iodized salt alone is insufficient to provide adequate requirements.
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