Evidence map›Paper›PMID 36839333›Full record

Trial reportNutrients2023

Effect of Supplementation with Black Chokeberry (

Błażej Stankiewicz, Mirosława Cieślicka, Jan Mieszkowski, Andrzej Kochanowicz, Bartłomiej Niespodziński, Andrzej Szwarc, Tomasz Waldziński, Joanna Reczkowicz, Elżbieta Piskorska, Miroslav Petr and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06254170 (Effect of Supplementation With Euterpe Edulis on the Physical and Mental Performance of Healthy Men Subjecting to Physical Exercise), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06254170 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Effect of Supplementation With Euterpe Edulis on the Physical and Mental Performance of Healthy Men Subjecting to Physical Exercise

TypeinterventionalSponsorUniversity Vila VelhaRan2024 to 2024Enrolled20ConditionsClinical TrialArmsEuterpe Edulis juice, Placebo
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. A Review ofFoods (Basel, Switzerland) · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Polyphenols, Polysaccharides, and Their Complexes fromMolecules (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Designing New Sport Supplements Based onMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Błażej StankiewiczInstitute of Physical Education, Kazimierz Wielki University, Jana Karola Chodkiewicza 30, 85-064 Bydgoszcz, Poland.ORCID 0000-0001-6743-1073
Mirosława CieślickaDepartment of Human Physiology, Nicolaus Copernicus University, Karłowicza 24, 85-092 Bydgoszcz, Poland.ORCID 0000-0002-0407-2592
Jan MieszkowskiDepartment of Gymnastics and Dance, Gdansk University of Physical Education and Sport, Kazimierza Gorskiego 1, 80-336 Gdansk, Poland.ORCID 0000-0001-6753-5139
Andrzej KochanowiczDepartment of Gymnastics and Dance, Gdansk University of Physical Education and Sport, Kazimierza Gorskiego 1, 80-336 Gdansk, Poland.
Bartłomiej NiespodzińskiInstitute of Physical Education, Kazimierz Wielki University, Jana Karola Chodkiewicza 30, 85-064 Bydgoszcz, Poland.ORCID 0000-0001-8992-3730
Andrzej SzwarcDepartment of Team Sports, Gdansk University of Physical Education and Sport, Kazimierza Gorskiego 1, 80-336 Gdansk, Poland.ORCID 0000-0003-1959-3902
Tomasz WaldzińskiFaculty of Health Sciences, Łomża State University of Applied Science, Akademicka 14, 18-400 Lomza, Poland.
Joanna ReczkowiczMedical Department of Bioenergetics and Physiology of Exercise, Faculty of Health Sciences, Medical University of Gdansk, Dębinki 1, 80-211 Gdansk, Poland.ORCID 0000-0002-9944-1687
Elżbieta PiskorskaDepartment of Pathobiochemistry and Clinical Chemistry, Nicolaus Copernicus University Collegium Medicum, M. Curie Skłodowskiej 9, 85-094 Bydgoszcz, Poland.
Miroslav PetrFaculty of Physical Education and Sport, Charles University, 162 52 Prague, Czech Republic.ORCID 0000-0001-8735-1935
Anna Skarpańska-StejnbornDepartment of Morphological and Health Sciences, Faculty of Physical Culture in Gorzow Wielkopolski, Poznan University of Physical Education, Orląt Lwowskich 4-6, 66-400 Gorzów Wielkopolski, Poland.
Jędrzej AntosiewiczMedical Department of Bioenergetics and Physiology of Exercise, Faculty of Health Sciences, Medical University of Gdansk, Dębinki 1, 80-211 Gdansk, Poland.ORCID 0000-0002-7871-6469

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of herbal medicinal products and supplements in amateur and professional sports has increased in the last decades. This is because most of these products and supplements contain bioactive compounds with a variety of biological properties that exert a physiological effect on the human body. The aim of this study was to analyze the effect of dietary supplementation with lyophilized black chokeberry extract on the levels of pro-inflammatory cytokines, hepcidin, and selected markers of iron metabolism in a group of young football players. This double-blind study included 22 male football players (mean = 19.96 ± 0.56), divided into two groups: supplemented and placebo. Before and after a 90-day period of training combined with supplementation (6 g of lyophilized black chokeberry extract), participants performed maximal multistage 20-m shuttle run tests at the beginning and at the end of the supplementation period, with blood sampled for analysis at different times before and after exercise. The levels of IL-6, IL-10, ferritin, myoglobin, hepcidin, 8-OHdG, albumin, and TAC were analyzed. The analysis of variance revealed a significant effect of 90-day supplementation with the lyophilized extract on changes in the IL-6 and IL-10 levels, and TAC induced by maximal aerobic effort. In conclusion, supplementation with lyophilized black chokeberry extract improves the performance and antioxidant status of serum in humans and induces protective changes in inflammatory markers.

Indexed as

Dietary SupplementsIronPhotiniaPlant ExtractsAthletesDouble-Blind MethodHepcidinsHumansInflammationInterleukin-10Interleukin-6MaleSoccerYoung AdultHepcidinsInterleukin-10Interleukin-6IronPlant Extractsblack chokeberry extractinflammationironreactive oxygen speciessupplementation

Identifiers

PMID36839333
PMCPMC9965193

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.