Evidence map›Paper›PMID 36839276›Full record

ArticleNutrients2023

Mediation of 10-Year Cardiovascular Disease Risk between Inflammatory Diet and Handgrip Strength: Base on NHANES 2011-2014.

Zechun Xie, Ling Wang, Mengzi Sun, Rui Wang, Jing Li, Xuhan Wang, Ruirui Guo, Yibo Dong, Yuxiang Wang, Bo Li

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Smoking promotes colorectal cancer via the CKAP2L/AREG axis.International journal of oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zechun XieDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Ling WangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Mengzi SunDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.ORCID 0000-0001-8001-8064
Rui WangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Jing LiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Xuhan WangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Ruirui GuoDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Yibo DongDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Yuxiang WangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Bo LiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.ORCID 0000-0003-1455-9596

Funding

National Natural Science Foundation of China No.81973129
6 · The paper itself

Abstract

objectiveDietary inflammatory index (DII) and handgrip strength (HGS) were correlated, and both were associated with cardiovascular disease (CVD). However, the role of the 10-year CVD risk in the relationship between DII and grip strength remains uncertain.

methodsThis study involved 5691 adults from the National Health and Nutrition Examination Survey (NHANES) in 2011-2014. Dietary inflammation, 10-year CVD risk and relative grip strength were assessed by the Dietary Inflammation Index, the Framingham Risk Score (FRS) and handgrip strength adjusted BMI. Linear regression analyses and mediation analysis were used to explore these associations.

resultsBoth DII and 10-year CVD risk were negatively associated with relative handgrip strength, and DII was positively associated with 10-year CVD risk. Additionally, 10-year CVD risk partially mediated the association between DII and relative handgrip strength by a 11.8% proportion. Specifically, the mediating effect of the 10-year risk of CVD varied by gender and age.

conclusionsReducing the 10-year risk of CVD attenuates the effect of an inflammatory diet on relative grip strength impairment. Therefore, we recommend reducing the effect of inflammatory diet on grip strength impairment by controlling any of the FRS parameters, such as lowering blood pressure and smoking cessation, especially with targeted measures for different populations.

Indexed as

Cardiovascular DiseasesAdultDietHand StrengthHumansInflammationNutrition SurveysRisk Factorscardiovascular diseasehandgrip strengthinflammatory dietmediationNHANES

Identifiers

PMID36839276
PMCPMC9962519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.