Evidence map›Paper›PMID 36839269›Full record

ReviewNutrients2023

Nuts and Cardiovascular Disease Outcomes: A Review of the Evidence and Future Directions.

Andrea J Glenn, Dagfinn Aune, Heinz Freisling, Noushin Mohammadifard, Cyril W C Kendall, Jordi Salas-Salvadó, David J A Jenkins, Frank B Hu, John L Sievenpiper

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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  17. Dietary Patterns in Asia: Current Evidence and Future Directions.Advances in nutrition (Bethesda, Md.) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 7 countries.

Andrea J GlennDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Dagfinn AuneDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0002-4533-1722
Heinz FreislingNutrition and Metabolism Branch, International Agency for Research on Cancer (IARC-WHO), 69366 Lyon, France.ORCID 0000-0001-8648-4998
Noushin MohammadifardIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID 0000-0003-1776-1060
Cyril W C KendallDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
Jordi Salas-SalvadóDepartment of Biochemistry & Biotechnology, School of Medicine, Institut d'Investigacions Sanitàries Pere i Virgili, Rovira i Virgili University, 43204 Reus, Spain.ORCID 0000-0003-2700-7459
David J A JenkinsDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.ORCID 0000-0003-1192-9571
Frank B HuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
John L SievenpiperDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
St. Michael's Hospital · CABrigham and Women's Hospital · USCentre international de recherche sur le cancer · FRInstituto de Salud Carlos III · ESIsfahan University of Medical Sciences · IROslo University Hospital · NO

Funding

CIHR N/AWorld Health Organization 001
6 · The paper itself

Abstract

Nuts are nutrient-rich foods that contain many bioactive compounds that are beneficial for cardiovascular health. Higher consumption of nuts has been associated with a reduced risk of several cardiovascular diseases (CVD) in prospective cohort studies, including a 19% and 25% lower risk of CVD incidence and mortality, respectively, and a 24% and 27% lower risk of coronary heart disease incidence and mortality, respectively. An 18% lower risk of stroke mortality, a 15% lower risk of atrial fibrillation, and a 19% lower risk of total mortality have also been observed. The role of nuts in stroke incidence, stroke subtypes, peripheral arterial disease and heart failure has been less consistent. This narrative review summarizes recommendations for nuts by clinical practice guidelines and governmental organizations, epidemiological evidence for nuts and CVD outcomes, nut-containing dietary patterns, potential mechanisms of nuts and CVD risk reduction, and future research directions, such as the use of biomarkers to help better assess nut intake. Although there are still some uncertainties around nuts and CVD prevention which require further research, as summarized in this review, there is a substantial amount of evidence that supports that consuming nuts will have a positive impact on primary and secondary prevention of CVD.

Indexed as

Cardiovascular DiseasesCoronary DiseaseStrokeHumansNutsProspective Studiescardiovascular diseasesnutritionpeanutsreviewtree nuts

Identifiers

PMID36839269
PMCPMC9964942
OpenAlexW4320491559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.