ArticleNutrients2023
The Geriatric Nutritional Risk Index (GNRI) as a Prognostic Biomarker for Immune Checkpoint Inhibitor Response in Recurrent and/or Metastatic Head and Neck Cancer.
Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 5 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 5 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Nutritional conditions and PFS and OS in cancer immunotherapy: the MOUSEION-010 meta-analysis.Immunotherapy · 2025Pooled it
- Pooled it
- Predictive value of geriatric nutritional risk index in patients with pancreatic cancer: a meta-analysis.Frontiers in nutrition · 2025Pooled it
- Efficacy of the Geriatric Nutritional Risk Index for Predicting Overall Survival in Patients with Head and Neck Cancer: A Meta-Analysis.Nutrients · 2023Pooled it
- Low geriatric nutritional risk index as a poor prognostic biomarker for immune checkpoint inhibitor treatment in solid cancer.Frontiers in nutrition · 2023Pooled it
- Safety and Exploratory Pre-Post Changes Associated with an Orally Disintegrating Three-Strain Probiotic Tablet in Older Adults with Functional Constipation: A Single-Center, Open-Label, Single-Arm Study.Diseases (Basel, Switzerland) · 2026Article
- Article
- Geriatric Nutritional Risk Index Predicts Treatment Intolerance and Survival in Head and Neck Cancer.Head & neck · 2026Article
- Neutrophil Percentage-to-Albumin Ratio as a Prognostic and Predictive Biomarker in Non-Metastatic Breast Cancer Treated with Neoadjuvant Chemotherapy: Findings from a Retrospective Cohort.Diagnostics (Basel, Switzerland) · 2026Article
- Clinical value of geriatric nutritional risk index and pan-immune-inflammation value in locally advanced gastric cancer receiving neoadjuvant chemotherapy.World journal of gastrointestinal oncology · 2026Article
- Baseline Nutritional Indices as Prognostic Indicators in Patients with Recurrent or Metastatic Nasopharyngeal Carcinoma Treated with the PD-L1 Inhibitor KL-A167: A Secondary Analysis of the KL-A167 Trial.Cancer management and research · 2026Article
- Safety and efficacy of PRaG therapy in elderly cancer patients.Immunotherapy advances · 2026Article
- The role of Geriatric Nutritional Risk Index in predicting adverse outcomes in patients with bloodstream infections: a retrospective study.BMC geriatrics · 2025Article
- Geriatric nutritional risk index as a predictor of outcomes in elderly patients undergoing percutaneous coronary intervention: An updated systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Article
- The prognostic significance of the geriatric nutritional risk index in postoperative parotid gland carcinoma.Scientific reports · 2025Article
- Geriatric Nutritional Risk Index as a prognostic marker for predicting survival outcomes in patients with UTUC after radical nephroureterectomy.Scientific reports · 2025Article
- Geriatric Nutritional Risk Index is an effective prognostic predictor for metastatic/recurrent or unresectable esophageal cancer receiving immunotherapy.Journal of gastrointestinal oncology · 2025Article
- Development of a predictive nomogram based on preoperative inflammation-nutrition-related markers for prognosis in locally advanced lip squamous cell carcinoma after surgical treatment.BMC oral health · 2025Article
- Nutritional status affects inflammatory responses and exacerbates the severity of pulmonary tuberculosis.Frontiers in cellular and infection microbiology · 2025Article
- The joint role of systemic immune-inflammation index and geriatric nutritional risk index in cancer survivors and their impact on all-cause mortality.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malnutrition is a frequent comorbidity in head and neck cancer patients and has been shown to impair immunotherapy response in other cancer types. The geriatric nutritional risk index (GNRI) assesses malnutrition using the patient's ideal weight, actual weight, and serum albumin. The aim of this study was to evaluate the prognostic relevance of malnutrition as determined by the GNRI for the response to immunotherapy in recurrent and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC). A total of 162 patients with R/M HNSCC who received immune checkpoint inhibitors were included. The associations between the GNRI and progression-free survival (PFS), overall survival (OS), and the disease control rate (DCR) were computed. Univariable analysis showed worse PFS for GNRI ≤ 98 (
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