Evidence map›Paper›PMID 36838972›Full record

ArticleMolecules (Basel, Switzerland)2023

Multicomponent Domino Cyclization of Ethyl Trifluoropyruvate with Methyl Ketones and Amino Alcohols as A New Way to γ-Lactam Annulated Oxazacycles.

Marina V Goryaeva, Olesya A Fefelova, Yanina V Burgart, Marina A Ezhikova, Mikhail I Kodess, Pavel A Slepukhin, Vasily S Gaviko, Victor I Saloutin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marina V GoryaevaPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Science (IOS UB RAS), Ekaterinburg 620108, Russia.ORCID 0000-0002-7853-688X
Olesya A FefelovaPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Science (IOS UB RAS), Ekaterinburg 620108, Russia.
Yanina V BurgartPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Science (IOS UB RAS), Ekaterinburg 620108, Russia.
Marina A EzhikovaPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Science (IOS UB RAS), Ekaterinburg 620108, Russia.
Mikhail I KodessPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Science (IOS UB RAS), Ekaterinburg 620108, Russia.
Pavel A SlepukhinPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Science (IOS UB RAS), Ekaterinburg 620108, Russia.ORCID 0000-0001-8132-9905
Vasily S GavikoM.N. Mikheev Institute of Metal Physics, Ural Branch of the Russian Academy of Sciences (IMP UB RAS), Ekaterinburg 620108, Russia.
Victor I SaloutinPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Science (IOS UB RAS), Ekaterinburg 620108, Russia.ORCID 0000-0003-1976-7861
Institute of Organic Synthesis · RUM.N. Mikheev Institute of Metal Physics · RU

Funding

Russian Science Foundation 21-13-00390
6 · The paper itself

Abstract

A new route to bicyclic γ-lactams was found, which was proposed as a three-component cyclization of ethyl trifluoropyruvate with methyl ketones and 1,2-, 1,3-amino alcohols. As a result, a series of trifluoromethyl-substituted tetrahydropyrrolo [2,1-

Indexed as

AcetoneLactamsAldehydesAmino AlcoholsKetonesMolecular StructurePyruvic AcidStereoisomerism3-hydroxybutanalAcetoneAldehydesAmino Alcoholsethyl trifluoropyruvateKetonesLactamsPyruvic Acidamino alcoholsethyl trifluoropyruvatemethyl ketonesmulticomponent domino cyclizationstetrahydropyrrolo[2,1-b]oxazinonestetrahydropyrrolo[2,1-b]oxazolonesγ-lactams

Identifiers

PMID36838972
PMCPMC9967980
OpenAlexW4321377073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.