Evidence map›Paper›PMID 36838955›Full record

ArticleMolecules (Basel, Switzerland)2023

Release Profiles of Carvacrol or Chlorhexidine of PLA/Graphene Nanoplatelets Membranes Prepared Using Electrospinning and Solution Blow Spinning: A Comparative Study.

Roberto Scaffaro, Luca Settanni, Emmanuel Fortunato Gulino

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Advances in Biomedical Applications of Solution Blow Spinning.International journal of molecular sciences · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Roberto ScaffaroDepartment of Engineering, University of Palermo, Viale delle Scienze, Ed. 6, 90128 Palermo, PA, Italy.ORCID 0000-0002-4830-0374
Luca SettanniDepartment of Agricultural, Food and Forestry Sciences, University of Palermo, Viale delle Scienze, Ed. 5, 90128 Palermo, PA, Italy.ORCID 0000-0001-7019-3598
Emmanuel Fortunato GulinoDepartment of Engineering, University of Palermo, Viale delle Scienze, Ed. 6, 90128 Palermo, PA, Italy.ORCID 0000-0002-0529-8841
University of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanofibrous membranes are often the core components used to produce devices for a controlled release and are frequently prepared by electrospinning (ES). However, ES requires high production times and costs and is not easy to scale. Recently, solution blow spinning (SBS) has been proposed as an alternative technique for the production of nanofibrous membranes. In this study, a comparison between these two techniques is proposed. Poly (lactic acid)-based nanofibrous membranes were produced by electrospinning (ES) and solution blow spinning (SBS) in order to evaluate the different effect of liquid (carvacrol, CRV) or solid (chlorhexidine, CHX) molecules addition on the morphology, structural properties, and release behavior. The outcomes revealed that both ES and SBS nanofibrous mat allowed for obtaining a controlled release up to 500 h. In detail, the lower wettability of the SBS system allowed for slowing down the CRV release kinetics, compared to the one obtained for ES membranes. On the contrary, with SBS, a faster CHX release can be obtained due to its more hydrophilic behavior. Further, the addition of graphene nanoplatelets (GNP) led to a decrease in wettability and allowed for a slowing down of the release kinetics in the whole of the systems.

Indexed as

GraphiteNanofibersChlorhexidineCymenesDelayed-Action PreparationsPolyesterscarvacrolChlorhexidineCymenesDelayed-Action PreparationsGraphitePolyestersantimicrobial activitycarvacrolchlorhexidinecontrolled releaseelectrospinninggraphene nanoplateletsnanofibrous membranessolution blow spinning

Identifiers

PMID36838955
PMCPMC9962789
OpenAlexW4321377211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.