Evidence map›Paper›PMID 36838927›Full record

ArticleMolecules (Basel, Switzerland)2023

A Meroterpenoid from Tibetan Medicine Induces Lung Cancer Cells Apoptosis through ROS-Mediated Inactivation of the AKT Pathway.

Yi Huang, Yun Huang, Ge Zhu, Bingzhi Zhang, Yujia Zhu, Bin Chen, Xiaoxia Gao, Jie Yuan

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi HuangKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou 510080, China.
Yun HuangSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Ge ZhuDepartment of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Bingzhi ZhangSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yujia ZhuSchool of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Bin ChenSouthern Laboratory of Ocean Science and Engineering, Zhuhai 519000, China.
Xiaoxia GaoSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Jie YuanKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou 510080, China.

Funding

a grant from the Natural Science Foundation of Guangdong Province, China 2022A1515011037Guangdong Marine Economy Development Special Project GDNRC[2022]35
6 · The paper itself

Abstract

As a traditional Tibetan medicine in China,

Indexed as

Antineoplastic AgentsLung NeoplasmsAnimalsApoptosisCell Line, TumorCell ProliferationHumansMedicine, Tibetan TraditionalMicePapaveraceaeProto-Oncogene Proteins c-aktReactive Oxygen SpeciesXenograft Model Antitumor AssaysAntineoplastic AgentsProto-Oncogene Proteins c-aktReactive Oxygen SpeciesAKTapoptosisD1399meroterpenoidROSTibetan medicine

Identifiers

PMID36838927
PMCPMC9963024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.