Evidence map›Paper›PMID 36838857›Full record

ArticleMolecules (Basel, Switzerland)2023

Molecular Modes of Action of an Aqueous

Luay J Rashan, Nadire Özenver, Joelle C Boulos, Mona Dawood, Wynand P Roos, Katrin Franke, Ioannis Papasotiriou, Ludger A Wessjohann, Heinz-Herbert Fiebig, Thomas Efferth

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Therapeutic assessment ofFrontiers in oncology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 5 countries.

Luay J RashanFrankincense Biodiversity Unit, Research Center, Dhofar University, Salalah 211, Oman.
Nadire ÖzenverDepartment of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, 55128 Mainz, Germany.ORCID 0000-0001-9561-8994
Joelle C BoulosDepartment of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, 55128 Mainz, Germany.ORCID 0000-0003-1359-2634
Mona DawoodDepartment of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, 55128 Mainz, Germany.
Wynand P RoosInstitute of Toxicology, Medical Center of the University Mainz, Obere Zahlbacher Straße 67, 55131 Mainz, Germany.ORCID 0000-0002-0474-7414
Katrin FrankeDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry (IPB), Weinberg 3, 06120 Halle, Germany.ORCID 0000-0003-3043-3571
Ioannis PapasotiriouResearch Genetic Cancer Centre (RGCC) International GmbH, 6300 Zug, Switzerland.ORCID 0000-0002-6145-946X
Ludger A WessjohannDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry (IPB), Weinberg 3, 06120 Halle, Germany.ORCID 0000-0003-2060-8235
Heinz-Herbert Fiebig4HF Biotec GmbH, 79108 Freiburg, Germany.
Thomas EfferthDepartment of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, 55128 Mainz, Germany.ORCID 0000-0002-2637-1681
Johannes Gutenberg University Mainz · DELeibniz Institute of Plant Biochemistry · DEDhofar University · OMInternational Breast Cancer Study Group · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer drug resistance remains a major obstacle in clinical oncology. As most anticancer drugs are of natural origin, we investigated the anticancer potential of a standardized cold-water leaf extract from

Indexed as

Antineoplastic AgentsNeoplasmsNeriumAnimalsCell Line, TumorHumansMolecular Docking SimulationPaclitaxelPlant ExtractsTubulinAntineoplastic AgentsPaclitaxelPlant ExtractsTubulinApocynaceaecardenolidescardiac glycosidemitotic spindle poisonphytotherapy

Identifiers

PMID36838857
PMCPMC9960564
OpenAlexW4321095491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.