Evidence map›Paper›PMID 36838773›Full record

ArticleMolecules (Basel, Switzerland)2023

Evaluation of Rhenium and Technetium-99m Complexes Bearing Quinazoline Derivatives as Potential EGFR Agents.

Konstantina Makrypidi, Christos Kiritsis, Ioanna Roupa, Sotiria Triantopoulou, Antonio Shegani, Maria Paravatou-Petsotas, Aristeidis Chiotellis, Maria Pelecanou, Minas Papadopoulos, Ioannis Pirmettis

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Development of AGT-7: An InnovativePharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. New Radiopharmaceutical Tracers in Breast Cancer Diagnosis and Therapy.Anti-cancer agents in medicinal chemistry · 2025
    Review
  4. Article
  5. Synthesis and Evaluation ofPharmaceutics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Konstantina MakrypidiInstitute of Nuclear and Radiological Sciences and Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.ORCID 0000-0002-2046-8941
Christos KiritsisInstitute of Nuclear and Radiological Sciences and Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.
Ioanna RoupaInstitute of Nuclear and Radiological Sciences and Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.
Sotiria TriantopoulouInstitute of Nuclear and Radiological Sciences and Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.
Antonio SheganiInstitute of Nuclear and Radiological Sciences and Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.ORCID 0000-0002-3379-3911
Maria Paravatou-PetsotasInstitute of Nuclear and Radiological Sciences and Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.
Aristeidis ChiotellisInstitute of Nuclear and Radiological Sciences and Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.ORCID 0000-0003-0052-8393
Maria PelecanouInstitute of Biosciences & Applications, NCSR "Demokritos", 15310 Athens, Greece.ORCID 0000-0002-7669-2424
Minas PapadopoulosInstitute of Nuclear and Radiological Sciences and Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.
Ioannis PirmettisInstitute of Nuclear and Radiological Sciences and Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.ORCID 0000-0003-4933-7723

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Τhe Epidermal Growth Factor Receptor tyrosine kinase inhibitor (EGFR-TKI) 6-amino-4-[(3-bromophenyl) amino]quinazoline was derivatized with 6-bromohexanoyl-chloride and coupled with the tridentate chelating agents N-(2-pyridylmethyl) aminoethyl acetic acid (PAMA) and

Indexed as

RheniumTechnetiumAnimalsCell LineCysteineErbB ReceptorsHumansMiceQuinazolinesRadiopharmaceuticalsTissue DistributionCysteineErbB ReceptorsQuinazolinesRadiopharmaceuticalsRheniumTechnetiumcysteineEGFRPAMArheniumtechnetium-99mTKItricarbonyl

Identifiers

PMID36838773
PMCPMC9960821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.