Evidence map›Paper›PMID 36838685›Full record

ArticleMolecules (Basel, Switzerland)2023

Efficacy of Hydroponically Cultivated Saffron in the Preservation of Retinal Pigment Epithelium.

Mattia Di Paolo, Francesca Corsi, Maria Maggi, Luca Nardi, Silvia Bisti, Ilaria Piano, Claudia Gargini

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Combination ofInternational journal of molecular sciences · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mattia Di PaoloDepartment of Ophthalmology and Visual Sciences, University of Louisville, Kentucky, KY 40202, USA.
Francesca CorsiDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-9350-7948
Maria MaggiHortus Novus srl, via Campo Sportivo 2, 67050 Canistro, Italy.ORCID 0000-0003-2474-4672
Luca NardiENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, Biotechnology and Agro-Industry Division, Casaccia Research Center, 00123 Rome, Italy.ORCID 0000-0003-3063-8067
Silvia BistiNational Institute of Biostructure and Biosystem (INBB), V. le Medaglie D'Oro 305, 00136 Roma, Italy.ORCID 0000-0003-4157-111X
Ilaria PianoDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-5073-7583
Claudia GarginiDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.

Funding

"IDROZAFF" project, funded by the Italian Ministry of Economic Development, Sustainable Growth Fund Horizon 2020" PON I&C 2014-2020; CUP B83D17001330008
6 · The paper itself

Abstract

Saffron treatment is a broad-spectrum therapy used for several retinal diseases, and its effectiveness depends on a particular molecular composition (REPRON

Indexed as

CrocusCell LineColoring AgentsHydrogen PeroxideOxidative StressReactive Oxygen SpeciesRetinal Pigment EpitheliumColoring AgentsHydrogen PeroxideReactive Oxygen SpeciesARPE-19hydroponicREPRON®retinal disease

Identifiers

PMID36838685
PMCPMC9962550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.