Evidence map›Paper›PMID 36838564›Full record

ArticleMolecules (Basel, Switzerland)2023

Neuroprotective Effects of Savinin on LPS-Induced Neuroinflammation In Vivo via Regulating MAPK/NF-κB Pathway and NLRP3 Inflammasome Activation.

Siqi Tang, Chunying Li, Zongwu Suo, Yi Xu, Kaixin Wei, Lei Zhao, Hao Huang, Xiangqian Liu, Dongxu Liu, Xiaojun Li

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Antioxidant and Anti-Inflammatory Activities of Methanol Extract ofInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Neuroprotective effects of hesperetin on HNutrition research and practice · 2023
    Article
  8. Impact of levetiracetam on cognitive impairment, neuroinflammation, oxidative stress, and neuronal apoptosis caused by lipopolysaccharides in rats.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Siqi TangNational Engineering Research Center for Modernization of Traditional Chinese Medicine-Hakka Medical Resources Branch, School of Pharmacy, Gannan Medical University, Ganzhou 341000, China.
Chunying LiCollege of Basic Medicine, Gannan Medical University, Ganzhou 341000, China.
Zongwu SuoNational Engineering Research Center for Modernization of Traditional Chinese Medicine-Hakka Medical Resources Branch, School of Pharmacy, Gannan Medical University, Ganzhou 341000, China.
Yi XuNational Engineering Research Center for Modernization of Traditional Chinese Medicine-Hakka Medical Resources Branch, School of Pharmacy, Gannan Medical University, Ganzhou 341000, China.
Kaixin WeiNational Engineering Research Center for Modernization of Traditional Chinese Medicine-Hakka Medical Resources Branch, School of Pharmacy, Gannan Medical University, Ganzhou 341000, China.
Lei ZhaoCollege of Basic Medicine, Gannan Medical University, Ganzhou 341000, China.
Hao HuangNational Engineering Research Center for Modernization of Traditional Chinese Medicine-Hakka Medical Resources Branch, School of Pharmacy, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0002-7788-5519
Xiangqian LiuSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.
Dongxu LiuCollege of Basic Medicine, Gannan Medical University, Ganzhou 341000, China.
Xiaojun LiNational Engineering Research Center for Modernization of Traditional Chinese Medicine-Hakka Medical Resources Branch, School of Pharmacy, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0001-7781-3710
Gannan Medical University · CNHunan University of Traditional Chinese Medicine · CN

Funding

Ganzhou Science and Technology Innovation Youth Talent Plan 202101094465Jiangxi Provincial Department of Education GJJ201538Jiangxi Provincial Key R & D project 20212BBG73041National Natural Science Foundation of China 82111530101
6 · The paper itself

Abstract

The traditional herb

Indexed as

LignansNeuroprotective AgentsAnimalsInflammasomesInflammationLipopolysaccharidesMaleMiceMice, Inbred C57BLNeuroinflammatory DiseasesNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinInflammasomesLignansLipopolysaccharidesNeuroprotective AgentsNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mousesavininMAPKneuroinflammationNF-κBNLRP3 inflammasomesavinin

Identifiers

PMID36838564
PMCPMC9962396
OpenAlexW4319441817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.