Evidence map›Paper›PMID 36838468›Full record

ArticleMicroorganisms2023

Broad-Spectrum Antimicrobial Activity of Oftasecur and Visuprime Ophthalmic Solutions.

Federica Dell'Annunziata, Maria Vittoria Morone, Marco Gioia, Ferdinando Cione, Massimiliano Galdiero, Nicola Rosa, Gianluigi Franci, Maddalena De Bernardo, Veronica Folliero

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Federica Dell'AnnunziataDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-1654-8500
Maria Vittoria MoroneDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.
Marco GioiaDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0002-4474-3020
Ferdinando CioneDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0002-1031-6434
Massimiliano GaldieroDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-1576-6290
Nicola RosaDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0002-2366-6556
Gianluigi FranciDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0003-3321-4331
Maddalena De BernardoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0003-4566-0064
Veronica FollieroDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-7406-9882
University of Salerno · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the wide etiology of conjunctivitis, the expensive and time-consuming diagnosis requires new therapeutic strategies with broad-spectrum antimicrobial activity and nonselective mechanisms of action. In this context, eye drops could provide an alternative to conventional antimicrobial therapies. Here, we compare the antibacterial and antiviral activity of Oftasecur and Visuprime, commercially available ophthalmic solutions. Cytotoxicity assay was performed on Vero CCL-81 cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) test. Antibacterial efficacy was evaluated on

Indexed as

antibacterial activityantiviral potentialeye dropsGram-negative bacteriaGram-positive bacteriaHSV-1OftasecurVisuprime

Identifiers

PMID36838468
PMCPMC9959165
OpenAlexW4321252248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.