Evidence map›Paper›PMID 36838456›Full record

ArticleMicroorganisms2023

Developmentally Programmed Switches in DNA Replication: Gene Amplification and Genome-Wide Endoreplication in

Xiangzhou Meng, Hung Quang Dang, Geoffrey M Kapler

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Endoreplication-Why Are We Not Using Its Full Application Potential?International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Xiangzhou MengDepartment of Cell Biology and Genetics, Texas A&M University Health Science Center, Bryan, TX 77807, USA.ORCID 0000-0003-2827-7661
Hung Quang DangDepartment of Cell Biology and Genetics, Texas A&M University Health Science Center, Bryan, TX 77807, USA.ORCID 0000-0002-1226-0235
Geoffrey M KaplerDepartment of Cell Biology and Genetics, Texas A&M University Health Science Center, Bryan, TX 77807, USA.
Texas A&M Health Science Center · US

Funding

National Science Foundation MCB-0132675
6 · The paper itself

Abstract

Locus-specific gene amplification and genome-wide endoreplication generate the elevated copy number of ribosomal DNA (rDNA, 9000 C) and non-rDNA (90 C) chromosomes in the developing macronucleus of

Indexed as

DNA replicationendoreplicationgene amplificationmacronuclear developmentTetrahymena thermophila

Identifiers

PMID36838456
PMCPMC9967165
OpenAlexW4321095312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.