ReviewMicroorganisms2023
The Potential Use of Fungal Co-Culture Strategy for Discovery of New Secondary Metabolites.
Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Enhanced terpenoid synthesis in Alternaria alstroemeriae PPL7 via co-fermentation with Paeonia lactiflora roots: integrated metabolomic and transcriptomic analysis.Archives of microbiology · 2026Article
- Co-cultures of Microalgae and Other Microorganisms: Wastewater Treatment and Production of Value-Added Bioproducts.Applied biochemistry and biotechnology · 2026Review
- From Contact to Stalemate: MAPK-Associated Chemical and Enzymatic Defenses Shape a Stable Barrage in the Co-Culture ofJournal of fungi (Basel, Switzerland) · 2026Article
- Co-Culture ofJournal of fungi (Basel, Switzerland) · 2025Article
- Article
- Analyzing the Challenges and Opportunities Associated With Harnessing New Antibiotics From the Fungal Microbiome.MicrobiologyOpen · 2025Review
- Article
- Engineering of Global Transcriptional Regulators (GTRs) inJournal of fungi (Basel, Switzerland) · 2025Review
- Unravelling fungal genome editing revolution: pathological and biotechnological application aspects.Archives of microbiology · 2025Review
- Lichens are a treasure chest of bioactive compounds: fact or fake?The New phytologist · 2025Article
- 5,6-Dihydro-5,6-Epoxymultiplolide A, Cytosporone C, and Uridine Production byMicroorganisms · 2025Article
- Last Decade Insights in Exploiting Marine Microorganisms as Sources of New Bioactive Natural Products.Marine drugs · 2025Review
- Assessment of microbial antagonistic activity and Quorum Sensing Signal Molecule (Cyclopeptides-DKPs and N-Acyl Homoserine Lactones) detection in bacterial strains obtained from avocado thrips (Thysanoptera: Thripidae).Biotechnology reports (Amsterdam, Netherlands) · 2025Article
- Harnessing the microbial interactions fromSynthetic and systems biotechnology · 2025Article
- Endophytic Fungi Co-Culture: An Alternative Source of Antimicrobial Substances.Microorganisms · 2024Review
- Volatile Organic Compounds Produced by Co-Culture ofInternational journal of molecular sciences · 2024Article
- Synergistic Biocontrol and Growth Promotion in Strawberries by Co-CulturedJournal of fungi (Basel, Switzerland) · 2024Article
- A mass spectrometry-based strategy for investigating volatile molecular interactions in microbial consortia: unveiling aFrontiers in microbiology · 2024Article
- Characterization and application of tannase and gallic acid produced by co-fungi of Aspergillus niger and Trichoderma viride utilizing agro-residues substrates.Scientific reports · 2023Article
- Exploring Diverse Bioactive Secondary Metabolites from Marine Microorganisms Using Co-Culture Strategy.Molecules (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Fungi are an important and prolific source of secondary metabolites (SMs) with diverse chemical structures and a wide array of biological properties. In the past two decades, however, the number of new fungal SMs by traditional monoculture method had been greatly decreasing. Fortunately, a growing number of studies have shown that co-culture strategy is an effective approach to awakening silent SM biosynthetic gene clusters (BGCs) in fungal strains to produce cryptic SMs. To enrich our knowledge of this approach and better exploit fungal biosynthetic potential for new drug discovery, this review comprehensively summarizes all fungal co-culture methods and their derived new SMs as well as bioactivities on the basis of an extensive literature search and data analysis. Future perspective on fungal co-culture study, as well as its interaction mechanism, is supplied.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.