Evidence map›Paper›PMID 36838398›Full record

ReviewMicroorganisms2023

Arthropod-Borne Flaviviruses in Pregnancy.

Annaleise R Howard-Jones, David Pham, Rebecca Sparks, Susan Maddocks, Dominic E Dwyer, Jen Kok, Kerri Basile

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Severe dengue in the intensive care unit.Journal of intensive medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Annaleise R Howard-JonesCentre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research-NSW Health Pathology, Westmead, NSW 2145, Australia.ORCID 0000-0002-9756-2813
David PhamCentre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research-NSW Health Pathology, Westmead, NSW 2145, Australia.ORCID 0000-0002-0953-4063
Rebecca SparksCentre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research-NSW Health Pathology, Westmead, NSW 2145, Australia.
Susan MaddocksCentre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research-NSW Health Pathology, Westmead, NSW 2145, Australia.ORCID 0000-0002-7843-551X
Dominic E DwyerCentre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research-NSW Health Pathology, Westmead, NSW 2145, Australia.ORCID 0000-0002-7163-2844
Jen KokCentre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research-NSW Health Pathology, Westmead, NSW 2145, Australia.ORCID 0000-0002-8796-283X
Kerri BasileCentre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research-NSW Health Pathology, Westmead, NSW 2145, Australia.ORCID 0000-0003-0647-4314
The University of Sydney · AUWestmead Institute for Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flaviviruses are a diverse group of enveloped RNA viruses that cause significant clinical manifestations in the pregnancy and postpartum periods. This review highlights the epidemiology, pathophysiology, clinical features, diagnosis, and prevention of the key arthropod-borne flaviviruses of concern in pregnancy and the neonatal period-Zika, Dengue, Japanese encephalitis, West Nile, and Yellow fever viruses. Increased disease severity during pregnancy, risk of congenital malformations, and manifestations of postnatal infection vary widely amongst this virus family and may be quite marked. Laboratory confirmation of infection is complex, especially due to the reliance on serology for which flavivirus cross-reactivity challenges diagnostic specificity. As such, a thorough clinical history including relevant geographic exposures and prior vaccinations is paramount for accurate diagnosis. Novel vaccines are eagerly anticipated to ameliorate the impact of these flaviviruses, particularly neuroinvasive disease manifestations and congenital infection, with consideration of vaccine safety in pregnant women and children pivotal. Moving forward, the geographical spread of flaviviruses, as for other zoonoses, will be heavily influenced by climate change due to the potential expansion of vector and reservoir host habitats. Ongoing 'One Health' engagement across the human-animal-environment interface is critical to detect and responding to emergent flavivirus epidemics.

Indexed as

Dengue virusflavivirusJapanese encephalitis virusneonatepregnancyWest Nile virusYellow fever virusZika virus

Identifiers

PMID36838398
PMCPMC9959669
OpenAlexW4319756363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.