Evidence map›Paper›PMID 36838209›Full record

ArticleMicroorganisms2023

Genetic, Antigenic, and Pathobiological Characterization of H9 and H6 Low Pathogenicity Avian Influenza Viruses Isolated in Vietnam from 2014 to 2018.

Kien Trung Le, Lam Thanh Nguyen, Loc Tan Huynh, Duc-Huy Chu, Long Van Nguyen, Tien Ngoc Nguyen, Tien Ngoc Tien, Keita Matsuno, Masatoshi Okamatsu, Takahiro Hiono and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Kien Trung LeLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.
Lam Thanh NguyenDepartment of Veterinary Medicine, College of Agriculture, Can Tho University, Can Tho 941-15, Vietnam.ORCID 0000-0002-3413-8281
Loc Tan HuynhLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.ORCID 0000-0001-9922-4802
Duc-Huy ChuDepartment of Animal Health, Ministry of Agriculture and Rural Development, Ha Noi 115-19, Vietnam.
Long Van NguyenDepartment of Animal Health, Ministry of Agriculture and Rural Development, Ha Noi 115-19, Vietnam.
Tien Ngoc NguyenDepartment of Animal Health, Ministry of Agriculture and Rural Development, Ha Noi 115-19, Vietnam.
Tien Ngoc TienRegional Animal Health Office VII, Department of Animal Health, Ministry of Agriculture and Rural Development, Can Tho 942-07, Vietnam.
Keita MatsunoLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.
Masatoshi OkamatsuLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.
Takahiro HionoLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.ORCID 0000-0001-8897-3592
Norikazu IsodaLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.ORCID 0000-0003-3480-988X
Yoshihiro SakodaLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.ORCID 0000-0001-7021-1688
Hokkaido University · JPMinistry of Agriculture and Rural Development · VNCan Tho University · VN

Funding

Japan Agency for Medical Research and Development JP18fm0108008Japan Agency for Medical Research and Development JP20jm0210054h0004Japan Agency for Medical Research and Development JP223fa627005Japan International Cooperation Agency JP20jm0110019Ministry of Education, Culture, Sports, Science and Technology the Doctoral Program for World-Leading Innovative & Smart Education (WISE)Ministry of Education, Culture, Sports, Science and Technology The International Priority Graduate ProgramsMinistry of Education, Culture, Sports, Science and Technology The Program for Leading Graduate Schools (F01)
6 · The paper itself

Abstract

The H9 and H6 subtypes of low pathogenicity avian influenza viruses (LPAIVs) cause substantial economic losses in poultry worldwide, including Vietnam. Herein, we characterized Vietnamese H9 and H6 LPAIVs to facilitate the control of avian influenza. The space-time representative viruses of each subtype were selected based on active surveillance from 2014 to 2018 in Vietnam. Phylogenetic analysis using hemagglutinin genes revealed that 54 H9 and 48 H6 Vietnamese LPAIVs were classified into the sublineages Y280/BJ94 and Group II, respectively. Gene constellation analysis indicated that 6 and 19 genotypes of the H9 and H6 subtypes, respectively, belonged to the representative viruses. The Vietnamese viruses are genetically related to the previous isolates and those in neighboring countries, indicating their circulation in poultry after being introduced into Vietnam. The antigenicity of these subtypes was different from that of viruses isolated from wild birds. Antigenicity was more conserved in the H9 viruses than in the H6 viruses. Furthermore, a representative H9 LPAIV exhibited systemic replication in chickens, which was enhanced by coinfection with avian pathogenic

Indexed as

coinfectionEscherichia coli O2low pathogenicity avian influenzapathogenicity assessmentsurveillanceVietnam

Identifiers

PMID36838209
PMCPMC9962344
OpenAlexW4317508170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.