Evidence map›Paper›PMID 36838166›Full record

ArticleMicromachines2023

Cost-Effective Droplet Generator for Portable Bio-Applications.

Lin Du, Yuxin Li, Jie Wang, Zijian Zhou, Tian Lan, Dalei Jing, Wenming Wu, Jia Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lin DuSchool of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200433, China.ORCID 0000-0001-7485-0030
Yuxin LiSchool of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200433, China.
Jie WangSchool of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200433, China.
Zijian ZhouSchool of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200433, China.
Tian LanSchool of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200433, China.
Dalei JingSchool of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200433, China.
Wenming WuInstitute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510075, China.ORCID 0000-0003-4793-6132
Jia ZhouState Key Laboratory of ASIC and System, School of Microelectronics, Fudan University, Shanghai 200433, China.ORCID 0000-0002-9098-5661

Funding

National Natural Science Foundation of China 62104148, 61874033State Key Laboratory of ASIC and System, Fudan University 2021KF001, 2021MS001
6 · The paper itself

Abstract

The convenient division of aqueous samples into droplets is necessary for many biochemical and medical analysis applications. In this article, we propose the design of a cost-effective droplet generator for potential bio-chemical application, featuring two symmetric tubes. The new droplet generator revisits the relationship between capillary components and liquid flow rates. The size of generated droplets by prototype depends only on generator dimensions, without precisely needing to control external flow conditions or driving pressure, even when the relative extreme difference in flow rate for generating nL level droplets is over 57.79%, and the relative standard deviation (RSD) of the volume of droplets is barely about 9.80%. A dropper working as a pressure resource is used to verify the rapidity and robustness of this principle of droplet generation, which shows great potential for a wide range of droplet-based applications.

Indexed as

capillary numberlab chipmicrodropletsqueezing model

Identifiers

PMID36838166
PMCPMC9966110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.