Evidence map›Paper›PMID 36838127›Full record

ReviewMicromachines2023

A Genosensor Based on the Modification of a Microcantilever: A Review.

He Zhang, Shuang Yang, Jian Zeng, Xin Li, Rongyan Chuai

Open access · goldAbstract readReview
In one paragraph

Review in Micromachines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Biosensors; nanomaterial-based methods in diagnosing ofJournal of clinical tuberculosis and other mycobacterial diseases · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

He ZhangSchool of Information Science and Engineering, Shenyang University of Technology, Shenyang 110870, China.ORCID 0000-0003-0371-9507
Shuang YangSchool of Information Science and Engineering, Shenyang University of Technology, Shenyang 110870, China.ORCID 0000-0002-9113-8456
Jian ZengSchool of Information Science and Engineering, Shenyang University of Technology, Shenyang 110870, China.
Xin LiSchool of Information Science and Engineering, Shenyang University of Technology, Shenyang 110870, China.
Rongyan ChuaiSchool of Information Science and Engineering, Shenyang University of Technology, Shenyang 110870, China.
Shenyang University of Technology · CN

Funding

2021 Young and Middle-aged Scientific and Technological Innovation Talent Support Program of Shenyang RC210032Fundamental Research Fund of Liaoning Provincial Education Department LJGD2020014
6 · The paper itself

Abstract

When the free end of a microcantilever is modified by a genetic probe, this sensor can be used for a wider range of applications, such as for chemical analysis, biological testing, pharmaceutical screening, and environmental monitoring. In this paper, to clarify the preparation and detection process of a microcantilever sensor with genetic probe modification, the core procedures, such as probe immobilization, complementary hybridization, and signal extraction and processing, are combined and compared. Then, to reveal the microcantilever's detection mechanism and analysis, the influencing factors of testing results, the theoretical research, including the deflection principle, the establishment and verification of a detection model, as well as environmental influencing factors are summarized. Next, to demonstrate the application results of the genetic-probe-modified sensors, based on the classification of detection targets, the application status of other substances except nucleic acid, virus, bacteria and cells is not introduced. Finally, by enumerating the application results of a genetic-probe-modified microcantilever combined with a microfluidic chip, the future development direction of this technology is surveyed. It is hoped that this review will contribute to the future design of a genetic-probe-modified microcantilever, with further exploration of the sensitive mechanism, optimization of the design and processing methods, expansion of the application fields, and promotion of practical application.

Indexed as

application fielddetection principleenvironmental impact factorsgenetic probemicrocantileversensitive modification

Identifiers

PMID36838127
PMCPMC9959632
OpenAlexW4320492827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.