Evidence map›Paper›PMID 36837920›Full record

ArticleMetabolites2023

Machine Learning-Based Integration of Metabolomics Characterisation Predicts Progression of Myopic Retinopathy in Children and Adolescents.

Xiao-Wen Hou, Jin-Liu-Xing Yang, Dan-Lin Li, Yi-Jin Tao, Chao-Fu Ke, Bo Zhang, Shang Liu, Tian-Yu Cheng, Tian-Xiao Wang, Xun Xu and 2 more

Abstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The application of artificial intelligence in myopia prediction for children and adolescents: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The potential role of amino acids in myopia: inspiration from metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2024
    Review
  8. Metabolic Characteristics of Sclera in Lens-Induced Myopic Guinea Pigs.Investigative ophthalmology & visual science · 2024
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiao-Wen HouSchool of Public Health, Medical College of Soochow University, Suzhou 215123, China.ORCID 0000-0001-5067-7966
Jin-Liu-Xing YangSchool of Public Health, Medical College of Soochow University, Suzhou 215123, China.
Dan-Lin LiSchool of Public Health, Medical College of Soochow University, Suzhou 215123, China.
Yi-Jin TaoDepartment of Ophthalmology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Chao-Fu KeSchool of Public Health, Medical College of Soochow University, Suzhou 215123, China.
Bo ZhangShanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Shanghai 200040, China.
Shang LiuShanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Shanghai 200040, China.
Tian-Yu ChengShanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Shanghai 200040, China.
Tian-Xiao WangShanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Shanghai 200040, China.
Xun XuShanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Shanghai 200040, China.
Xian-Gui HeShanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Shanghai 200040, China.
Chen-Wei PanSchool of Public Health, Medical College of Soochow University, Suzhou 215123, China.ORCID 0000-0003-3362-4613

Funding

National Key R&D Program of China 2021YFC2702103National Natural Science Foundation of China 81973061National Natural Science Foundation of China 82122059National Natural Science Foundation of China 82260215
6 · The paper itself

Abstract

Myopic retinopathy is an important cause of irreversible vision loss and blindness. As metabolomics has recently been successfully applied in myopia research, this study sought to characterize the serum metabolic profile of myopic retinopathy in children and adolescents (4-18 years) and to develop a diagnostic model that combines clinical and metabolic features. We selected clinical and serum metabolic data from children and adolescents at different time points as the training set (

Indexed as

children and adolescentsmachine learningmetabolomicsmyopic retinopathyprediction model

Identifiers

PMID36837920
PMCPMC9965721

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.