Evidence map›Paper›PMID 36837890›Full record

ArticleMetabolites2023

Diet Quality and Liver Health in People Living with HIV in the MASH Cohort: A Multi-Omic Analysis of the Fecal Microbiome and Metabolome.

Haley R Martin, Sabrina Sales Martinez, Vitalii Stebliankin, Javier A Tamargo, Adriana Campa, Giri Narasimhan, Jacqueline Hernandez, Jose A Bastida Rodriguez, Colby Teeman, Angelique Johnson and 2 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Haley R MartinRobert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th Street, AHC-5 500, Miami, FL 33199, USA.ORCID 0000-0002-1850-7390
Sabrina Sales MartinezRobert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th Street, AHC-5 500, Miami, FL 33199, USA.ORCID 0000-0002-0158-8104
Vitalii StebliankinBioinformatics Research Group (BioRG), School of Computing and Information Sciences, University Park Campus, Florida International University, ECS-254, Miami, FL 33199, USA.ORCID 0000-0001-9377-0263
Javier A TamargoRobert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th Street, AHC-5 500, Miami, FL 33199, USA.
Adriana CampaRobert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th Street, AHC-5 500, Miami, FL 33199, USA.ORCID 0000-0001-8448-6033
Giri NarasimhanBioinformatics Research Group (BioRG), School of Computing and Information Sciences, University Park Campus, Florida International University, ECS-254, Miami, FL 33199, USA.ORCID 0000-0003-0535-4871
Jacqueline HernandezRobert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th Street, AHC-5 500, Miami, FL 33199, USA.ORCID 0000-0002-6741-8124
Jose A Bastida RodriguezRobert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th Street, AHC-5 500, Miami, FL 33199, USA.
Colby TeemanRobert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th Street, AHC-5 500, Miami, FL 33199, USA.
Angelique JohnsonRobert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th Street, AHC-5 500, Miami, FL 33199, USA.
Kenneth E ShermanDepartment of Internal Medicine, Division of Digestive Diseases, College of Medicine, University of Cincinnati, 3230 Eden Ave, Cincinnati, OH 45267, USA.
Marianna K BaumRobert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th Street, AHC-5 500, Miami, FL 33199, USA.ORCID 0000-0002-6577-685X
Florida International University · USUniversity of Cincinnati · US

Funding

The FIU Research Center in a Minority Institution (FIU-RCMI)U54MD012393 · NIMHD · FLORIDA INTERNATIONAL UNIVERSITY · PI ERIC F WAGNER · 2017 to 2026
$32.1M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Temitope O. Keku · 1985 to 2026
$30.5M
Community-Engaged Research on COVID-19 Testing Among Underserved and/or Vulnerable PopulationsU01DA040381 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI BAUM, MARIANNA K · 2015 to 2022
$9.6M
Community-Engaged Research on COVID-19 Testing Among Underserved and/or Vulnerable Populations Phase IIU01MD017423 · NIMHD · FLORIDA INTERNATIONAL UNIVERSITY · PI BAUM, MARIANNA K · 2022 to 2023
$2.2M
NIDA NIH HHS U01 DA040381NIDA NIH HHS U01-DA040381NIDDK NIH HHS P30 DK034987NIDDK NIH HHS P30 DK056350NIMHD NIH HHS 1U01MD017423NIMHD NIH HHS U01 MD017423NIMHD NIH HHS U54 MD012393NIMHD NIH HHS U54-MD012393
6 · The paper itself

Abstract

The gut-liver axis has been recognized as a potential pathway in which dietary factors may contribute to liver disease in people living with HIV (PLWH). The objective of this study was to explore associations between dietary quality, the fecal microbiome, the metabolome, and liver health in PLWH from the Miami Adult Studies on HIV (MASH) cohort. We performed a cross-sectional analysis of 50 PLWH from the MASH cohort and utilized the USDA Healthy Eating Index (HEI)-2015 to measure diet quality. A Fibrosis-4 Index (FIB-4) score < 1.45 was used as a strong indication that advanced liver fibrosis was not present. Stool samples and fasting blood plasma samples were collected. Bacterial composition was characterized using 16S rRNA sequencing. Metabolomics in plasma were determined using gas and liquid chromatography/mass spectrometry. Statistical analyses included biomarker identification using linear discriminant analysis effect size. Compared to participants with FIB-4 ≥ 1.45, participants with FIB-4 < 1.45 had higher intake of dairy (

Indexed as

dietdiet qualityHealthy Eating IndexHIVliver diseasemetabolomemetabolomicsmicrobiomenutrition

Identifiers

PMID36837890
PMCPMC9962547
OpenAlexW4320919598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.