Evidence map›Paper›PMID 36837882›Full record

ArticleMetabolites2023

Salivary Metabolomic Analysis Reveals Amino Acid Metabolism Shift in SARS-CoV-2 Virus Activity and Post-Infection Condition.

Tatiana Kelly da Silva Fidalgo, Liana Bastos Freitas-Fernandes, Barbara Bruno Fagundes Marques, Caroline Souza de Araújo, Bruno Jefferson da Silva, Taísa Coelho Guimarães, Ricardo Guimarães Fischer, Eduardo Muniz Barretto Tinoco, Ana Paula Valente

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. LongitudinalViruses · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tatiana Kelly da Silva FidalgoDepartment of Preventive and Community Dentistry, School of Dentistry, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20551-030, Brazil.ORCID 0000-0003-1340-9967
Liana Bastos Freitas-FernandesNational Center for Nuclear Magnetic Resonance, Medical Biochemistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.
Barbara Bruno Fagundes MarquesDepartment of Periodontology, School of Dentistry, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20551-030, Brazil.ORCID 0000-0003-0876-8607
Caroline Souza de AraújoDepartment of Preventive and Community Dentistry, School of Dentistry, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20551-030, Brazil.
Bruno Jefferson da SilvaNational Center for Nuclear Magnetic Resonance, Medical Biochemistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.ORCID 0000-0001-6357-5707
Taísa Coelho GuimarãesDepartment of Periodontology, School of Dentistry, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20551-030, Brazil.
Ricardo Guimarães FischerDepartment of Periodontology, School of Dentistry, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20551-030, Brazil.
Eduardo Muniz Barretto TinocoDepartment of Periodontology, School of Dentistry, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20551-030, Brazil.
Ana Paula ValenteNational Center for Nuclear Magnetic Resonance, Medical Biochemistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.ORCID 0000-0001-7219-1123
Universidade do Estado do Rio de Janeiro · BRUniversidade Federal do Rio de Janeiro · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro CNEFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro JCNENational Council for Scientific and Technological Development Produtividade em Pesquisa - PQ
6 · The paper itself

Abstract

The SARS-CoV-2 virus primarily infects salivary glands suggesting a change in the saliva metabolite profile; this shift may be used as a monitoring instrument during SARS-CoV-2 infection. The present study aims to determine the salivary metabolomic profile of patients with and post-SARS-CoV-19 infection. Patients were without (PCR-), with SARS-CoV-2 (PCR+), or post-SARS-CoV-2 infection. Unstimulated whole saliva was collected, and the

Indexed as

COVID-19metabolomicsnuclear magnetic resonancePCRpost-COVID-19salivaSARS-CoV-2

Identifiers

PMID36837882
PMCPMC9962089
OpenAlexW4320492445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.