Evidence map›Paper›PMID 36837850›Full record

ArticleMetabolites2023

Quercetin Induces Apoptosis in HepG2 Cells

Hui Guan, Wenyuan Zhang, Hui Liu, Yang Jiang, Feng Li, Maoyu Wu, Geoffrey I N Waterhouse, Dongxiao Sun-Waterhouse, Dapeng Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. The YYR (YY1- RKIP) Regulatory Axis in the pathogenesis of Cancer and Immune Evasion.Journal of experimental & clinical cancer research : CR · 2025
    Review
  8. Review
  9. Antioxidants (Basel, Switzerland) · 2025
    Article
  10. Article
  11. A tailored 4GRSC advances · 2025
    Article
  12. Article
  13. Review
  14. Liver cancer wars: plant-derived polyphenols strike back.Medical oncology (Northwood, London, England) · 2024
    Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Hui GuanKey Laboratory of Food Processing Technology and Quality Control of Shandong Higher Education Institutes, College of Food Science and Engineering, Shandong Agricultural University, 61 Dai Zong Street, Tai'an 271018, China.
Wenyuan ZhangKey Laboratory of Food Processing Technology and Quality Control of Shandong Higher Education Institutes, College of Food Science and Engineering, Shandong Agricultural University, 61 Dai Zong Street, Tai'an 271018, China.
Hui LiuKey Laboratory of Food Processing Technology and Quality Control of Shandong Higher Education Institutes, College of Food Science and Engineering, Shandong Agricultural University, 61 Dai Zong Street, Tai'an 271018, China.
Yang JiangKey Laboratory of Food Processing Technology and Quality Control of Shandong Higher Education Institutes, College of Food Science and Engineering, Shandong Agricultural University, 61 Dai Zong Street, Tai'an 271018, China.
Feng LiKey Laboratory of Food Processing Technology and Quality Control of Shandong Higher Education Institutes, College of Food Science and Engineering, Shandong Agricultural University, 61 Dai Zong Street, Tai'an 271018, China.ORCID 0000-0003-0611-2735
Maoyu WuJinan Fruit Research Institute of All China Federation of Supply & Marketing Cooperatives, 16001 East Road Jingshi, Jinan 250220, China.
Geoffrey I N WaterhouseSchool of Chemical Sciences, The University of Auckland, Auckland 0632, New Zealand.ORCID 0000-0002-3296-3093
Dongxiao Sun-WaterhouseKey Laboratory of Food Processing Technology and Quality Control of Shandong Higher Education Institutes, College of Food Science and Engineering, Shandong Agricultural University, 61 Dai Zong Street, Tai'an 271018, China.
Dapeng LiKey Laboratory of Food Processing Technology and Quality Control of Shandong Higher Education Institutes, College of Food Science and Engineering, Shandong Agricultural University, 61 Dai Zong Street, Tai'an 271018, China.ORCID 0000-0002-1816-3217
Shandong Agricultural University · CNUniversity of Auckland · NZFruit Research Institute · CN

Funding

High-level foreign experts project G2022023018LKey Research & Development Project of Shandong Province 2021TZXD007National Natural Science Foundation of China 31972070, 31571836the Shandong "Double Tops" Program SYT2017XTTD04
6 · The paper itself

Abstract

Quercetin is a flavonol found in edible plants and possesses a significant anticancer activity. This study explored the mechanism by which quercetin prevented liver cancer

Indexed as

anticancerapoptosisbinding competitionquercetin-YY1 interactionYY1-p53 binding

Identifiers

PMID36837850
PMCPMC9968089
OpenAlexW4319317270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.