Evidence map›Paper›PMID 36837844›Full record

ArticleMetabolites2023

Projections from the Rostral Zona Incerta to the Thalamic Paraventricular Nucleus Mediate Nociceptive Neurotransmission in Mice.

Feng-Ling Wu, Si-Hai Chen, Jia-Ni Li, Liu-Jie Zhao, Xue-Mei Wu, Jie Hong, Ke-Hua Zhu, Han-Xue Sun, Su-Juan Shi, E Mao and 4 more

Abstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. The pPVTThe journal of headache and pain · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Microglial adenosine AFrontiers in pharmacology · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Feng-Ling WuDepartment of Human Anatomy, College of Preclinical Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0002-2782-6676
Si-Hai ChenDepartment of Human Anatomy, College of Preclinical Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0002-9632-4098
Jia-Ni LiDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0003-4405-0029
Liu-Jie ZhaoDepartment of Human Anatomy, College of Preclinical Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0002-2862-9500
Xue-Mei WuDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0002-2765-4341
Jie HongDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0003-4132-2236
Ke-Hua ZhuDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0002-4009-2558
Han-Xue SunDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0001-8404-725X
Su-Juan ShiDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0001-8380-9531
E MaoDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0001-8539-7067
Wei-Dong ZangDepartment of Human Anatomy, College of Preclinical Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0001-8365-4672
Jing CaoDepartment of Human Anatomy, College of Preclinical Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0003-3124-4780
Zhen-Zhen KouDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0003-2624-8146
Yun-Qing LiDepartment of Human Anatomy, College of Preclinical Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0002-3707-3348

Funding

Innovation Capability Support Program of Shaanxi 2021TD-57Li Yunqing Expert Workstation of Yunnan Province 202005AF150014National Natural Science Foundation of China 82130034,82221001,81971035National Natural Science Foundation of Shaanxi 2019SF-083National Science and Technology Innovation 2030 Major Program 2021ZD0204403
6 · The paper itself

Abstract

Zona incerta (ZI) is an integrative subthalamic region in nociceptive neurotransmission. Previous studies demonstrated that the rostral ZI (ZIR) is an important gamma-aminobutyric acid-ergic (GABAergic) source to the thalamic paraventricular nucleus (PVT), but whether the ZIR-PVT pathway participates in nociceptive modulation is still unclear. Therefore, our investigation utilized anatomical tracing, fiber photometry, chemogenetic, optogenetic and local pharmacological approaches to investigate the roles of the ZIR

Indexed as

GABA-A receptorgamma–aminobutyric acid-ergicnociceptive neurotransmissionthalamic paraventricular nucleuszona incerta

Identifiers

PMID36837844
PMCPMC9966812

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.