Evidence map›Paper›PMID 36837802›Full record

ArticleMetabolites2023

Untargeted Metabolomics Revealed Potential Biomarkers of Small Yellow Follicles of Chickens during Sexual Maturation.

Jinbo Zhao, Hongbin Pan, Wenjiang Zhao, Wei Li, Haojie Li, Zhongxiao Tian, Dayong Meng, Yuting Teng, Xinlu Li, Yang He and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jinbo ZhaoFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Hongbin PanFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Wenjiang ZhaoBranch of Animal Husbandry and Veterinary of Heilongjiang Academy of Agricultural Sciences, Qiqihar 161005, China.
Wei LiBranch of Animal Husbandry and Veterinary of Heilongjiang Academy of Agricultural Sciences, Qiqihar 161005, China.
Haojie LiFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Zhongxiao TianFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Dayong MengFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Yuting TengFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Xinlu LiFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Yang HeFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Hongmei ShiFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Changrong GeFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Kun WangFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Yunnan Agricultural University · CNHeilongjiang Provincial Academy of Agricultural Sciences · CN

Funding

National System for Layer Production Technology CARS-40-S25the Major Science and Technology Project of Joint Funds of the National Natural Science Founda-tion of China U2002205Yunnan Su Zhengchang Expert Workstation 20149IC008Yunnan Xichou black bone chicken Industry science and technology mission 202104BI090020
6 · The paper itself

Abstract

Sexual maturation provides economically important traits in poultry production. Research on the initiation mechanism of sexual maturity is of great significance for breeding high-yield laying hens. However, the underlying mechanisms are not fully clear. Here, one hundred and fifty Chahua No. 2 laying hens (the CH2 group, which has precocious puberty) and one hundred and fifty Wu Liang Shan black-bone laying hens (the WLS group, a late-maturing chicken breed) with similar weights and ages were randomly selected. ELISA was used to determine the secretion levels of luteinizing hormone (LH), estradiol (E2), and progesterone (P4) in 150-day-old serum and small yellow follicle (SYF) tissues. A histology examination, immunohistochemistry, and quantitative real-time PCR (qPCR) were used to explore the molecular mechanism of how some genes related to oxidative stress affect sexual maturation. The results showed that the secretion levels of LH, E2, and P4 in the CH2 group serum and SYF were higher than those in the WLS group. The results of the real-time PCR of all genes showed that the expression levels of cytochrome P450 family 11 subfamily A member 1, steroidogenic acute regulatory protein, follicle-stimulating hormone receptor, and cytochrome P450 family 19 subfamily A member 1 in the CH2 group were significantly higher than those in the WLS groups (

Indexed as

differentially expressed metabolites and metabolic pathwaysferroptosismTOR signaling pathwaypotential biomarkerssexual maturationsmall yellow folliclesuntargeted metabolomics

Identifiers

PMID36837802
PMCPMC9964950
OpenAlexW4318206215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.