ArticleMetabolites2023
Effect of Methionine Hydroxy Analog on Hu Sheep Digestibility, Rumen Fermentation, and Rumen Microbial Community In Vitro.
Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Dietary Hydroxy-Selenomethionine Improves Antioxidant Status and Reduces Somatic Cell Count in Dairy Cows: Multi-Omics Insights into Rumen Microbiota and Metabolic Profiles.Antioxidants (Basel, Switzerland) · 2026Article
- A preliminary metagenomic and metabolomic investigation into the effects of Aspergillus niger cultures on microbial homeostasis and antibiotic resistance gene profiles in the rumen of fattening sheep.Journal of animal science and biotechnology · 2026Article
- Effects of wilting and additives on fermentation characteristics, microbial composition, metabolome, and ruminal degradation properties of mulberry silage.BMC microbiology · 2026Article
- Integrated multi-omics reveals the impact of ruminal keystone bacteria and microbial metabolites on average daily gain in Xuzhou cattle.Microbiology spectrum · 2025Article
- Article
- Rumen microbiota succession throughout the perinatal period and its association with postpartum production traits in dairy cows: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- Article
- Differential responses of rumen and fecal fermentation and microbiota of Liaoning cashmere goats after 2-hydroxy-4-(methylthio) butanoic acid isopropyl ester supplementation.Scientific reports · 2024Article
- Temporal dynamics of volatile fatty acids profile, methane production, and prokaryotic community in anFrontiers in microbiology · 2024Article
- Article
- Effects of yeast culture and oxalic acid supplementation onFrontiers in veterinary science · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This experiment was conducted to evaluate the effects of a methionine hydroxy analog (MHA) on in vitro gas production, rumen fermentation parameters, and rumen microbiota. Two different MHA, 2-hydroxy-4-(methylthio) butanoic acid isopropyl ester (HMBi) and the calcium salt of the hydroxy analog of methionine (MHA-Ca), were selected for in vitro experiments. The treatments were the Control group (0% of MHA), HMBi group (2%HMBi), and MHA-Ca group (2%MHA-Ca). Dry matter digestibility was measured after 12 h and 24 h of fermentation, and fermentation parameters and microbial composition were analyzed after 24 h. HMBi and MHA-Ca showed increased (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.