Evidence map›Paper›PMID 36837769›Full record

ArticleMetabolites2023

Optimized Fast Filtration-Based Sampling and Extraction Enables Precise and Absolute Quantification of the

Lilja Brekke Thorfinnsdottir, Laura García-Calvo, Gaute Hovde Bø, Per Bruheim, Lisa Marie Røst

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  6. Review
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  11. Tryptophan extends the life of cytochrome P450.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Activation of multiple stress responses inFrontiers in microbiology · 2023
    Article
  13. Survival ofFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lilja Brekke ThorfinnsdottirDepartment of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, N-7491 Trondheim, Norway.ORCID 0000-0002-1838-3439
Laura García-CalvoDepartment of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, N-7491 Trondheim, Norway.ORCID 0000-0002-9885-9854
Gaute Hovde BøDepartment of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, N-7491 Trondheim, Norway.
Per BruheimDepartment of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, N-7491 Trondheim, Norway.ORCID 0000-0002-7851-8083
Lisa Marie RøstDepartment of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, N-7491 Trondheim, Norway.ORCID 0000-0003-3980-8667
Norwegian University of Science and Technology · NO

Funding

Norwegian University of Science and Technology Internal funding from Department of Biotechnology and Food ScienceNorwegian University of Science and Technology Internal funding from Faculty of Natural ScienceTrond Mohn Foundation TMS2019TMT05
6 · The paper itself

Abstract

Precise and accurate quantification is a prerequisite for interpretation of targeted metabolomics data, but this task is challenged by the inherent instability of the analytes. The sampling, quenching, extraction, and sample purification conditions required to recover and stabilize metabolites in representative extracts have also been proven highly dependent on species-specific properties. For

Indexed as

absolute metabolite quantificationadenylate energy chargecentral carbon metabolismEscherichia colifast filtration samplingintracellular metabolite concentrationsmass spectrometrymetabolite extractiontargeted metabolite profiling

Identifiers

PMID36837769
PMCPMC9965072
OpenAlexW4317425952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.