Evidence map›Paper›PMID 36836907›Full record

ArticleLife (Basel, Switzerland)2023

Enzymatic Hydrolysis of Rutin: Evaluation of Kinetic Parameters and Anti-Proliferative, Mutagenic and Anti-Mutagenic Effects.

Mariana Alves Sobreiro, Adriana Della Torre, Maria Elisa Melo Branco de Araújo, Paula Renata Bueno Campos Canella, João Ernesto de Carvalho, Patrícia de Oliveira Carvalho, Ana Lucia Tasca Gois Ruiz

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mariana Alves SobreiroHealth Sciences Postgraduate Program, Universidade São Francisco (USF), Bragança Paulista 12916-900, SP, Brazil.
Adriana Della TorreLaboratory of Phytochemistry and Experimental Pharmacology and Toxicology (LAFTEX), Faculty of Pharmaceutical Sciences, University of Campinas, 200 Candido Portinari Street, Campinas 13083-871, SP, Brazil.
Maria Elisa Melo Branco de AraújoHealth Sciences Postgraduate Program, Universidade São Francisco (USF), Bragança Paulista 12916-900, SP, Brazil.
Paula Renata Bueno Campos CanellaHealth Sciences Postgraduate Program, Universidade São Francisco (USF), Bragança Paulista 12916-900, SP, Brazil.ORCID 0000-0002-4244-713X
João Ernesto de CarvalhoLaboratory of Phytochemistry and Experimental Pharmacology and Toxicology (LAFTEX), Faculty of Pharmaceutical Sciences, University of Campinas, 200 Candido Portinari Street, Campinas 13083-871, SP, Brazil.
Patrícia de Oliveira CarvalhoHealth Sciences Postgraduate Program, Universidade São Francisco (USF), Bragança Paulista 12916-900, SP, Brazil.ORCID 0000-0002-2681-7022
Ana Lucia Tasca Gois RuizLaboratory of Phytochemistry and Experimental Pharmacology and Toxicology (LAFTEX), Faculty of Pharmaceutical Sciences, University of Campinas, 200 Candido Portinari Street, Campinas 13083-871, SP, Brazil.ORCID 0000-0002-0844-8702
Universidade São Francisco · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Financing Code 001National Council for Scientific and Technological Development #313440/2019-0São Paulo Research Foundation #2013/13196-0, #2011/12394-8, #2011/03540-0, #2011/01114-4, #2009/09224-3, #2009/08689-2
6 · The paper itself

Abstract

The bioavailability of glucoside flavonoids is influenced by the nature of the sugar, glucosides being absorbed faster than rhamnoglucosides, for example. One strategy to enhance the bioavailability is enzymatic hydrolysis. In this study, some kinetic parameters of hesperidinase-mediated hydrolysis of rutin were evaluated using an UHPLC/QTOF-MS

Indexed as

genotoxicity testhesperidinasequercetin-3-O-glucoside

Identifiers

PMID36836907
PMCPMC9967632
OpenAlexW4321096111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.